Diffuse midline gliomas (DMGs), including diffuse intrinsic pontine glioma, have among the
highest mortality rates of all childhood cancers, despite recent advancements in cancer …

Diffuse intrinsic pontine glioma (DIPG) is a type of intrinsic brainstem glial tumor that occurs
primarily in the pediatric population. DIPG is initially diagnosed based on clinical symptoms …

Abstract Introduction Diffuse midline gliomas (DMGs) are infiltrative midline gliomas
harboring H3K27M mutations and are generally associated with poor outcomes. H3K27M …

Abstract Introduction H3 K27M-mutated diffuse midline gliomas (H3-DMGs) are aggressive
tumors with a fatal outcome. This study integrating individual patient data (IPD) from …

OBJECTIVE The prognostic significance and genetic characteristics of H3 K27M–mutant
diffuse midline gliomas (DMGs) in different anatomical locations requires further clarification …

Introduction Pediatric and adult H3 K27M-mutant midline gliomas have variable clinical
presentations, prognoses, and molecular backgrounds. In this study, we integrated data from …

Adult tumors diagnosed as cerebellar glioblastoma (cGBM) are rare and their optimal
classification remains to be determined. The aim of this study was to identify subgroups of …

Adult brainstem gliomas (BSGs) are a group of rare central nervous system tumors with
varying prognoses and controversial standard treatment strategies. To provide an overview …

Introduction Diffuse midline gliomas (DMG) with the H3 K27M-mutation are a well-described
entity with most DMG harboring this mutation, with notable heterogeneity in adults. No …

Background With the recent advent of genetic testing, IDH-mutant glioma has been found
among adult brainstem gliomas. However, the clinical outcome and prognosis of IDH-mutant …