Pathogenic enteric viruses are a major cause of morbidity and mortality, particularly among
children in developing countries. The host response to enteric viruses occurs primarily within …

Implementation of inactivated polio vaccines (IPV) containing Sabin strains (sIPV) will further
enable global polio eradication efforts by improving vaccine safety during use and …

Comment 714 www. thelancet. com Vol 400 September 3, 2022 risk of vaccine-associated
paralytic poliomyelitis caused by Sabin 2. 6 Although most countries eliminated Sabinlike …

Background A longitudinal study was performed to determine the breadth, kinetics, and
correlations of systemic and mucosal antibody responses to severe acute respiratory …

COVID-19 is still prevalent around the globe. Although some SARS-CoV-2 vaccines have
been distributed to the population, the shortcomings of vaccines and the continuous …

Kefir consists of a large number of probiotics, which can regulate or shape the balance of
intestinal microbiota, and enhance the host's immune response. Kefir microbiota can shape …

Secretory immunoglobulin A (SIgA) regulates the composition and function of the gut
microbiota and modulates its interaction with the host, but how this regulation is achieved is …

Prior modeling studies showed that current outbreak management strategies are unlikely to
stop outbreaks caused by type 1 wild polioviruses (WPV1) or circulating vaccine-derived …

For more than 20 years, the World Health Organization Western Pacific Region (WPR) has
been polio-free. However, two current challenges are still polio-related. First, around half of …

Eradication of poliomyelitis globally is constrained by fecal shedding of live polioviruses,
both wild-type and vaccine-derived strains, into the environment. Although inactivated polio …