Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …

Abstract Rationale: The Notch and transforming growth factor-β (TGFβ) signaling pathways
are two intracellular mechanisms that control fibrosis in general but whether they play a …

Posterior segment eye diseases are a major cause of visual impairment worldwide. If left
untreated, most of them lead to partial or complete blindness. The formation of new …

Under physiological conditions, retinal pigment epithelium (RPE) is a cellular monolayer
composed of mitotically quiescent cells. Tight junctions and adherens junctions maintain the …

This study was aim to investigate whether the progression of proliferative vitreoretinopathy
(PVR) depended on the activation of Yes‐associated protein (YAP) and the subsequent …

Purpose The purpose of this study was to evaluate the effect and mechanism of quercetin on
TGF-β1-induced retinal pigment epithelial (RPE) cell proliferation, migration, and …

Purpose The main characteristic of proliferative vitreoretinopathy (PVR) is migration,
adhesion, and epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells …

Age-related macular degeneration (AMD), which is the leading cause of blindness among
the elderly in western societies, is majorly accompanied by retinal pigment epithelium (RPE) …

Background/Aims: Proliferative vitreoretinopathy (PVR) is a common refractory eye disease
that causes blindness and occurs after retinal detachment or retinal reattachment. Epidermal …

Serious proliferative vitreoretinopathy (PVR) may lead to vision loss or blindness due to the
generation of PVR membrane in vitreous and retina and tractional retinal detachment, it is …