[HTML][HTML] Treatment options for COVID-19: The reality and challenges

SS Jean, PI Lee, PR Hsueh - Journal of microbiology, immunology and …, 2020 - Elsevier
An outbreak related to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
was first reported in Wuhan, China in December 2019. An extremely high potential for …

[HTML][HTML] Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and …

CC Lai, YH Liu, CY Wang, YH Wang, SC Hsueh… - Journal of Microbiology …, 2020 - Elsevier
Since the emergence of coronavirus disease 2019 (COVID-19)(formerly known as the 2019
novel coronavirus [2019-nCoV]) in Wuhan, China in December 2019, which is caused by …

[HTML][HTML] Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS-CoV-2 agents?

CC Lai, CY Wang, PR Hsueh - Journal of Microbiology, Immunology and …, 2020 - Elsevier
Co-infection has been reported in patients with severe acute respiratory syndrome (SARS)
and Middle East respiratory syndrome, but there is limited knowledge on co-infection among …

[HTML][HTML] Structure of replicating SARS-CoV-2 polymerase

HS Hillen, G Kokic, L Farnung, C Dienemann… - Nature, 2020 - nature.com
The new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses
an RNA-dependent RNA polymerase (RdRp) for the replication of its genome and the …

[HTML][HTML] A critical overview of computational approaches employed for COVID-19 drug discovery

EN Muratov, R Amaro, CH Andrade, N Brown… - Chemical Society …, 2021 - pubs.rsc.org
COVID-19 has resulted in huge numbers of infections and deaths worldwide and brought
the most severe disruptions to societies and economies since the Great Depression …

[HTML][HTML] The 2019–2020 novel coronavirus (severe acute respiratory syndrome coronavirus 2) pandemic: A joint american college of academic international medicine …

SP Stawicki, R Jeanmonod, AC Miller… - Journal of global …, 2020 - journals.lww.com
What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in
December 2019, was later determined to be coronavirus disease 2019 (COVID-19). The …

Inter nation social lockdown versus medical care against COVID-19, a mild environmental insight with special reference to India

B Paital, K Das, SK Parida - Science of the total environment, 2020 - Elsevier
Abstract Infection by coronavirus (CoV-19) has led to emergence of a pandemic called as
Coronavirus Disease (COVID-19) that has so far affected about 210 countries. The dynamic …

SARS-CoV-2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for …

M Costanzo, MAR De Giglio… - Current medicinal …, 2020 - ingentaconnect.com
Here we report on the most recent updates on experimental drugs successfully employed in
the treatment of the disease caused by SARS-CoV-2 coronavirus, also referred to as COVID …

Estimating epidemiologic dynamics from cross-sectional viral load distributions

JA Hay, L Kennedy-Shaffer, S Kanjilal, NJ Lennon… - Science, 2021 - science.org
Estimating an epidemic's trajectory is crucial for developing public health responses to
infectious diseases, but case data used for such estimation are confounded by variable …

FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
In December 2019, a novel SARS-CoV-2 coronavirus emerged, causing an outbreak of life-
threatening pneumonia in the Hubei province, China, and has now spread worldwide …