Immunotherapies for hepatocellular carcinoma
JM Llovet, F Castet, M Heikenwalder… - Nature reviews Clinical …, 2022 - nature.com
Liver cancer, more specifically hepatocellular carcinoma (HCC), is the second leading
cause of cancer-related death and its incidence is increasing globally. Around 50% of …
cause of cancer-related death and its incidence is increasing globally. Around 50% of …
Advances in immunotherapy for hepatocellular carcinoma
B Sangro, P Sarobe, S Hervás-Stubbs… - Nature reviews …, 2021 - nature.com
Hepatocellular carcinoma (HCC) is a prevalent disease with a progression that is modulated
by the immune system. Systemic therapy is used in the advanced stage and until 2017 …
by the immune system. Systemic therapy is used in the advanced stage and until 2017 …
The immunological and metabolic landscape in primary and metastatic liver cancer
X Li, P Ramadori, D Pfister, M Seehawer… - Nature Reviews …, 2021 - nature.com
The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …
[HTML][HTML] Guidelines for the diagnosis and treatment of hepatocellular carcinoma (2019 edition)
J Zhou, H Sun, Z Wang, W Cong, J Wang, M Zeng… - Liver cancer, 2020 - karger.com
Background: Primary liver cancer, around 90% are hepatocellular carcinoma in China, is the
fourth most common malignancy and the second leading cause of tumor-related death …
fourth most common malignancy and the second leading cause of tumor-related death …
The liver cancer immune microenvironment: Therapeutic implications for hepatocellular carcinoma
R Donne, A Lujambio - Hepatology, 2023 - journals.lww.com
The liver is the sixth most common site of primary cancer in humans and the fourth leading
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …
Neutrophils as potential therapeutic targets in hepatocellular carcinoma
The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options
In light of a global rise in obesity and type 2 diabetes, non-alcoholic fatty liver disease
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …
Evidence-based management of hepatocellular carcinoma: systematic review and meta-analysis of randomized controlled trials (2002–2020)
PK Haber, M Puigvehí, F Castet, V Lourdusamy… - Gastroenterology, 2021 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer-related
mortality, with a rapidly changing landscape of treatments. In the past 20 years, numerous …
mortality, with a rapidly changing landscape of treatments. In the past 20 years, numerous …
Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells
Immune-based therapies such as immune checkpoint inhibitors have revolutionized the
systemic treatment of various cancer types. The therapeutic application of monoclonal …
systemic treatment of various cancer types. The therapeutic application of monoclonal …
Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open …
Background No adjuvant treatment has been established for patients who remain at high
risk for hepatocellular carcinoma recurrence after curative-intent resection or ablation. We …
risk for hepatocellular carcinoma recurrence after curative-intent resection or ablation. We …