Leishmaniasis is a widespread disease that causes 20,000 to 30,000 deaths annually,
making it a major health problem in endemic areas. Because of low-performance …

Leishmaniasis is a neglected tropical disease caused by a protozoan species of the genus
Leishmania affecting mostly the developing countries. The disease with current mortality rate …

The leishmaniases represent a public health problem in under-developed countries and are
considered a neglected disease by the World Health Organization (WHO). They are cuased …

The utilization of nanotechnology has brought about notable advancements in the field of
pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and …

Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide.
Although chemotherapy has been widely used to treat this disease, problems related to the …

Parasitic diseases are a neglected and serious problem, especially in underdeveloped
countries. Among the major parasitic diseases, Leishmaniasis figures as an urgent …

Nanomedicine strategies were first adapted and successfully translated to clinical
application for diseases, such as cancer and diabetes. These strategies would no doubt …

In this work, we report the antileishmanial activity of 15 compounds based on 2-pyrimidinyl
hydrazone and N-acylhydrazone derivatives, being 13 new compounds. All compounds …

Abstract Treatment of visceral leishmaniasis (VL) is compromised by drug toxicity, high cost
and/or the emergence of resistant strains. Though canine vaccines are available, there are …

Visceral leishmaniasis is an infectious disease caused by the protozoan Leishmania. Due to
the lack of vaccines and the limitations of current treatment (toxicity, serious adverse effects …