The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Abstract IL-12 and IL-23 are closely related cytokines with important roles in the regulation of
tissue inflammation. Converging evidence from studies in mice, human observational …

PURPOSE Clonal hematopoiesis (CH) can be transmitted from a donor to a recipient during
allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is …

CD40 is a TNF receptor superfamily member expressed on both immune and non-immune
cells. Interactions between B cell-expressed CD40 and its binding partner, CD40L …

Interleukin-12 is considered a potent agent to enhance antitumor immune responses. It
belongs to a family of heterodimeric cytokines with key roles in the up-regulation and down …

Antibiotics are by far the most common medications prescribed for children. Recent
epidemiological data suggests an association between early antibiotic use and disease …

The significance of the essential trace element zinc for immune function has been known for
several decades. Zinc deficiency affects immune cells, resulting in altered host defense …

Natural killer (NK) cells are effective in combating infections and tumors and as such are
tempting for adoptive transfer therapy. However, they are not homogeneous but can be …

Chimeric antigen receptor (CAR) T cells provide great efficacy in B cell malignancies.
However, improved CAR T cell therapies are still needed. Here, we engineered tumor …

ABSTRACT A major advantage of DNA vaccination is the ability to induce both humoral and
cellular immune responses. DNA vaccines are currently used in veterinary medicine, but …