Functional architecture of the retina: development and disease

M Hoon, H Okawa, L Della Santina… - Progress in retinal and eye …, 2014 - Elsevier
Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

Feature detection by retinal ganglion cells

D Kerschensteiner - Annual review of vision science, 2022 - annualreviews.org
Retinal circuits transform the pixel representation of photoreceptors into the feature
representations of ganglion cells, whose axons transmit these representations to the brain …

Connectomic reconstruction of the inner plexiform layer in the mouse retina

M Helmstaedter, KL Briggman, SC Turaga, V Jain… - Nature, 2013 - nature.com
Comprehensive high-resolution structural maps are central to functional exploration and
understanding in biology. For the nervous system, in which high resolution and large spatial …

Retinal waves prime visual motion detection by simulating future optic flow

X Ge, K Zhang, A Gribizis, AS Hamodi, AM Sabino… - Science, 2021 - science.org
INTRODUCTION Fundamental circuit features of the mouse visual system emerge before
the onset of vision, allowing the mouse to perceive objects and detect visual motion …

Space–time wiring specificity supports direction selectivity in the retina

JS Kim, MJ Greene, A Zlateski, K Lee, M Richardson… - Nature, 2014 - nature.com
How does the mammalian retina detect motion? This classic problem in visual neuroscience
has remained unsolved for 50 years. In search of clues, here we reconstruct Off-type …

Wiring specificity in the direction-selectivity circuit of the retina

KL Briggman, M Helmstaedter, W Denk - Nature, 2011 - nature.com
The proper connectivity between neurons is essential for the implementation of the
algorithms used in neural computations, such as the detection of directed motion by the …

Architecture, function, and assembly of the mouse visual system

TA Seabrook, TJ Burbridge, MC Crair… - Annual review of …, 2017 - annualreviews.org
Vision is the sense humans rely on most to navigate the world, make decisions, and perform
complex tasks. Understanding how humans see thus represents one of the most …

Mechanisms and functions of GABA co-release

NX Tritsch, AJ Granger, BL Sabatini - Nature Reviews Neuroscience, 2016 - nature.com
The'one neuron, one neurotransmitter'doctrine states that synaptic communication between
two neurons occurs through the release of a single chemical transmitter. However, recent …

Common circuit design in fly and mammalian motion vision

A Borst, M Helmstaedter - Nature neuroscience, 2015 - nature.com
Motion-sensitive neurons have long been studied in both the mammalian retina and the
insect optic lobe, yet striking similarities have become obvious only recently. Detailed …

Direction selectivity in the retina: symmetry and asymmetry in structure and function

DI Vaney, B Sivyer, WR Taylor - Nature Reviews Neuroscience, 2012 - nature.com
Visual information is processed in the retina to a remarkable degree before it is transmitted
to higher visual centres. Several types of retinal ganglion cells (the output neurons of the …