Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …

The success of linezolid stimulated significant efforts to discover new agents in the
oxazolidinone class. Over a dozen oxazolidinones have reached the clinic, but many were …

Production of a red blood cell's hemoglobin depends on mitochondrial heme synthesis.
However, mature red blood cells are devoid of mitochondria and rely on glycolysis for ATP …

Tuberculosis is an ancient human disease, estimated to have originated and evolved over
thousands of years alongside modern human populations. Despite considerable advances …

Background. Sepsis is associated with mitochondrial dysfunction and impaired oxygen
consumption, which may condition clinical outcome independent of tissue oxygenation …

Tedizolid, a novel oxazolidinone with activity against a wide range of Gram-positive
pathogens, was evaluated in two noninferiority phase 3 acute bacterial skin and skin …

The objective of the present retrospective observational study carried out in patients
receiving a standard dosage of linezolid and undergoing routine therapeutic drug …

Silver nanoparticles (AgNPs) are extensively used for their antibacterial properties in a
diverse set of applications, ranging from the treatment of municipal wastewater to infection …

Introduction Fibromyalgia is a chronic pain syndrome with unknown etiology. Recent studies
have shown some evidence demonstrating that oxidative stress may have a role in the …

Long-term linezolid use is limited by mitochondrial toxicity-associated adverse events (AEs).
Within a prospective, randomized controlled trial of linezolid to treat chronic extensively drug …