Etiology and therapeutic approach to elevated lactate levels
LW Andersen, J Mackenhauer, JC Roberts… - Mayo Clinic …, 2013 - Elsevier
Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …
the context of evaluating shock, lactate levels can be elevated for many reasons. While …
The oxazolidinones: past, present, and future
KJ Shaw, MR Barbachyn - Annals of the New York Academy of …, 2011 - Wiley Online Library
The success of linezolid stimulated significant efforts to discover new agents in the
oxazolidinone class. Over a dozen oxazolidinones have reached the clinic, but many were …
oxazolidinone class. Over a dozen oxazolidinones have reached the clinic, but many were …
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
M Kundu, T Lindsten, CY Yang, J Wu… - Blood, The Journal …, 2008 - ashpublications.org
Production of a red blood cell's hemoglobin depends on mitochondrial heme synthesis.
However, mature red blood cells are devoid of mitochondria and rely on glycolysis for ATP …
However, mature red blood cells are devoid of mitochondria and rely on glycolysis for ATP …
Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives
Tuberculosis is an ancient human disease, estimated to have originated and evolved over
thousands of years alongside modern human populations. Despite considerable advances …
thousands of years alongside modern human populations. Despite considerable advances …
The effects of sepsis on mitochondria
Background. Sepsis is associated with mitochondrial dysfunction and impaired oxygen
consumption, which may condition clinical outcome independent of tissue oxygenation …
consumption, which may condition clinical outcome independent of tissue oxygenation …
Analysis of the phase 3 ESTABLISH trials of tedizolid versus linezolid in acute bacterial skin and skin structure infections
AF Shorr, TP Lodise, GR Corey… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Tedizolid, a novel oxazolidinone with activity against a wide range of Gram-positive
pathogens, was evaluated in two noninferiority phase 3 acute bacterial skin and skin …
pathogens, was evaluated in two noninferiority phase 3 acute bacterial skin and skin …
Therapeutic drug monitoring of linezolid: a retrospective monocentric analysis
F Pea, M Furlanut, P Cojutti, F Cristini… - Antimicrobial agents …, 2010 - Am Soc Microbiol
The objective of the present retrospective observational study carried out in patients
receiving a standard dosage of linezolid and undergoing routine therapeutic drug …
receiving a standard dosage of linezolid and undergoing routine therapeutic drug …
A systematic review of evidence for silver nanoparticle-induced mitochondrial toxicity
Silver nanoparticles (AgNPs) are extensively used for their antibacterial properties in a
diverse set of applications, ranging from the treatment of municipal wastewater to infection …
diverse set of applications, ranging from the treatment of municipal wastewater to infection …
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease
MD Cordero, M De Miguel… - Arthritis research & …, 2010 - Springer
Introduction Fibromyalgia is a chronic pain syndrome with unknown etiology. Recent studies
have shown some evidence demonstrating that oxidative stress may have a role in the …
have shown some evidence demonstrating that oxidative stress may have a role in the …
Linezolid trough concentrations correlate with mitochondrial toxicity-related adverse events in the treatment of chronic extensively drug-resistant tuberculosis
Long-term linezolid use is limited by mitochondrial toxicity-associated adverse events (AEs).
Within a prospective, randomized controlled trial of linezolid to treat chronic extensively drug …
Within a prospective, randomized controlled trial of linezolid to treat chronic extensively drug …