Phenotypic plasticity enables individuals to develop different phenotypes in a changing
environment and promotes adaptive evolution. Genome-wide association study (GWAS) …

High-throughput genotyping technologies (such as SNP-arrays) allow the rapid collection of
up to a few million genetic markers of an individual. Detecting epistasis (based on 2-SNP …

Background Part of the missing heritability in Genome Wide Association Studies (GWAS) is
expected to be explained by interactions between genetic variants, also called epistasis …

Phenotypic plasticity is the exhibition of various phenotypic traits produced by a single
genotype in response to environmental changes, enabling organisms to adapt to …

We study the problem of rank aggregation: given a set of ranked lists, we want to form a
consensus ranking. Furthermore, we consider the case of extreme lists: ie, only the rank of …

Potential biomarker detection is a crucial area of study for the prediction, diagnosis, and
monitoring of Alzheimer's disease (AD). The voxelwise genome-wide association study …

The evolution of resistance to one antimicrobial can result in enhanced sensitivity to another,
known as “collateral sensitivity.” This underexplored phenomenon opens new therapeutic …

Deep Neural Networks and Embedding Methods in Drugs Interactions Analysis Page 1 Deep
Neural Networks and Embedding Methods in Drugs Interactions Analysis LIU, Pengfei A Thesis …

Abstract GENOME-wide Association Studies (GWAS) are increasingly popular in screening
the genetic architecture of human genome. For a typical GWAS study, half a million genetic …

With the development of next generation sequencing technology, researchers are able to
obtain extremely high-dimensional data. However, only a fraction of the data is related to …