According to the latest Global Burden of Disease Study data, non-communicable diseases in
general and cardiovascular disease (CVD) in particular are the leading cause of premature …

Vitamin K2 serves an important role in cardiovascular health through regulation of calcium
homeostasis. Its effects on the cardiovascular system are mediated through activation of the …

Background There is insufficient evidence for the ability of vitamin K2 to improve type 2
diabetes mellitus symptoms by regulating gut microbial composition. Herein, we aimed to …

Background Long‐term feeding with a high‐fat diet (HFD) induces endothelial dysfunction in
mice, but early HFD‐induced effects on endothelium have not been well characterized …

Recent studies have highlighted the importance of vitamin K2 (VK2) in human health.
However, there have been no clinical studies investigating the role of VK2 in the prevention …

Endothelial dysfunction is one of the hallmarks of vascular abnormalities in metabolic
diseases and has been repeatedly demonstrated in coronary and peripheral circulation in …

Although defined by the presence of airflow obstruction and respiratory symptoms, patients
with chronic obstructive pulmonary disease (COPD) are characterized by multimorbidity …

Osteocalcin (OCN) is a bone‐derived and vitamin K dependent hormone that affects energy
metabolism and vascular calcification. The relationship between serum OCN and vascular …

Vitamin K2/Menaquinones produced predominantly by the gut microbiome improve bone
health and prevent coronary calcification. The central nervous system has been linked with …

Cardiovascular disease (CVD) remains the leading cause of mortality in patients with type 2
diabetes (T2D). The conventional therapies seem to offer minimal long-term cardioprotection …