miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools
LJ Galvão-Lima, AHF Morais, RAM Valentim… - Biomedical engineering …, 2021 - Springer
Over the last decades, microRNAs (miRNAs) have emerged as important molecules
associated with the regulation of gene expression in humans and other organisms …
associated with the regulation of gene expression in humans and other organisms …
The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer
J Qu, Q Mei, L Liu, T Cheng, P Wang… - … in medical oncology, 2021 - journals.sagepub.com
The use of programmed cell-death protein 1 (PD-1)/programmed cell-death ligand 1 (PD-L1)
inhibitors is the standard therapy for the first-line or second-line treatment of patients with …
inhibitors is the standard therapy for the first-line or second-line treatment of patients with …
Oncobiology and treatment of breast cancer in young women
R Kumar, C Abreu, M Toi, S Saini, S Casimiro… - Cancer and Metastasis …, 2022 - Springer
Female breast cancer emerged as the leading cancer type in terms of incidence globally in
2020. Although mortality due to breast cancer has improved during the past three decades …
2020. Although mortality due to breast cancer has improved during the past three decades …
Perspectives on the role of histone modification in breast cancer progression and the advanced technological tools to study epigenetic determinants of metastasis
J Zhuang, Q Huo, F Yang, N Xie - Frontiers in Genetics, 2020 - frontiersin.org
Metastasis is a complex process that involved in various genetic and epigenetic alterations
during the progression of breast cancer. Recent evidences have indicated that the mutation …
during the progression of breast cancer. Recent evidences have indicated that the mutation …
Extracellular vesicles in breast cancer: from biology and function to clinical diagnosis and therapeutic management
S Loric, JA Denis, C Desbene, M Sabbah… - International journal of …, 2023 - mdpi.com
Breast cancer (BC) is the first worldwide most frequent cancer in both sexes and the most
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …
The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk
F Grassmann, A Mälarstig, L Dahl, A Bendes… - British Journal of …, 2024 - nature.com
Objective Current breast cancer risk prediction scores and algorithms can potentially be
further improved by including molecular markers. To this end, we studied the association of …
further improved by including molecular markers. To this end, we studied the association of …
Label-free breast cancer detection and classification by convolutional neural network-based on exosomes surface-enhanced raman scattering
Because the breast cancer is an important factor that threatens women's lives and health,
early diagnosis is helpful for disease screening and a good prognosis. Exosomes are …
early diagnosis is helpful for disease screening and a good prognosis. Exosomes are …
Methodological development of combination drug and radiotherapy in basic and clinical research
Newer technical improvements in radiation oncology have been rapidly implemented in
recent decades, allowing an improved therapeutic ratio. The development of strategies …
recent decades, allowing an improved therapeutic ratio. The development of strategies …
Mxi1 participates in the progression of lung cancer via the microRNA-300/KLF9/GADD34 Axis
Y Lei, Y Huang, J Lin, S Sun, K Che, J Shen… - Cell death & …, 2022 - nature.com
The purpose of the current study was to define the role of MAX interactor 1 (Mxi1) in the
pathogenesis of lung cancer and its underlying molecular mechanism. Bioinformatics …
pathogenesis of lung cancer and its underlying molecular mechanism. Bioinformatics …
Biological role and clinical implications of microRNAs in BRCA mutation carriers
C Tommasi, B Pellegrino, D Boggiani, A Sikokis… - Frontiers in …, 2021 - frontiersin.org
Women with pathogenic germline mutations in BRCA1 and BRCA2 genes have an
increased risk to develop breast and ovarian cancer. There is, however, a high interpersonal …
increased risk to develop breast and ovarian cancer. There is, however, a high interpersonal …