miRNAs as biomarkers for early cancer detection and their application in the development of new diagnostic tools

LJ Galvão-Lima, AHF Morais, RAM Valentim… - Biomedical engineering …, 2021 - Springer
Over the last decades, microRNAs (miRNAs) have emerged as important molecules
associated with the regulation of gene expression in humans and other organisms …

The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer

J Qu, Q Mei, L Liu, T Cheng, P Wang… - … in medical oncology, 2021 - journals.sagepub.com
The use of programmed cell-death protein 1 (PD-1)/programmed cell-death ligand 1 (PD-L1)
inhibitors is the standard therapy for the first-line or second-line treatment of patients with …

Oncobiology and treatment of breast cancer in young women

R Kumar, C Abreu, M Toi, S Saini, S Casimiro… - Cancer and Metastasis …, 2022 - Springer
Female breast cancer emerged as the leading cancer type in terms of incidence globally in
2020. Although mortality due to breast cancer has improved during the past three decades …

Perspectives on the role of histone modification in breast cancer progression and the advanced technological tools to study epigenetic determinants of metastasis

J Zhuang, Q Huo, F Yang, N Xie - Frontiers in Genetics, 2020 - frontiersin.org
Metastasis is a complex process that involved in various genetic and epigenetic alterations
during the progression of breast cancer. Recent evidences have indicated that the mutation …

Extracellular vesicles in breast cancer: from biology and function to clinical diagnosis and therapeutic management

S Loric, JA Denis, C Desbene, M Sabbah… - International journal of …, 2023 - mdpi.com
Breast cancer (BC) is the first worldwide most frequent cancer in both sexes and the most
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …

The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk

F Grassmann, A Mälarstig, L Dahl, A Bendes… - British Journal of …, 2024 - nature.com
Objective Current breast cancer risk prediction scores and algorithms can potentially be
further improved by including molecular markers. To this end, we studied the association of …

Label-free breast cancer detection and classification by convolutional neural network-based on exosomes surface-enhanced raman scattering

X Ma, H Xiong, J Guo, Z Liu, Y Han, M Liu… - Journal of Innovative …, 2023 - World Scientific
Because the breast cancer is an important factor that threatens women's lives and health,
early diagnosis is helpful for disease screening and a good prognosis. Exosomes are …

Methodological development of combination drug and radiotherapy in basic and clinical research

C Chargari, A Levy, X Paoletti, JC Soria… - Clinical Cancer …, 2020 - AACR
Newer technical improvements in radiation oncology have been rapidly implemented in
recent decades, allowing an improved therapeutic ratio. The development of strategies …

Mxi1 participates in the progression of lung cancer via the microRNA-300/KLF9/GADD34 Axis

Y Lei, Y Huang, J Lin, S Sun, K Che, J Shen… - Cell death & …, 2022 - nature.com
The purpose of the current study was to define the role of MAX interactor 1 (Mxi1) in the
pathogenesis of lung cancer and its underlying molecular mechanism. Bioinformatics …

Biological role and clinical implications of microRNAs in BRCA mutation carriers

C Tommasi, B Pellegrino, D Boggiani, A Sikokis… - Frontiers in …, 2021 - frontiersin.org
Women with pathogenic germline mutations in BRCA1 and BRCA2 genes have an
increased risk to develop breast and ovarian cancer. There is, however, a high interpersonal …