Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes

MB Gorbet, MV Sefton - The Biomaterials: Silver Jubilee Compendium, 2004 - Elsevier
Our failure to produce truly non-thrombogenic materials may reflect a failure to fully
understand the mechanisms of biomaterial-associated thrombosis. The community has …

Endotoxin: the uninvited guest

MB Gorbet, MV Sefton - Biomaterials, 2005 - Elsevier
In the laboratory environment where biomaterials are synthesized and their biocompatibility
assessed, we find that endotoxin contamination is hard to avoid and must not be ignored. In …

Cardiopulmonary bypass duration is an independent predictor of morbidity and mortality after cardiac surgery

S Salis, VV Mazzanti, G Merli, L Salvi… - Journal of cardiothoracic …, 2008 - Elsevier
OBJECTIVE: The purpose of this study was to find out if there is a direct relationship
between the duration of cardiopulmonary bypass (CPB time [CPBT]) and postoperative …

Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure

A Sandek, I Bjarnason, HD Volk, R Crane… - International journal of …, 2012 - Elsevier
BACKGROUND: Small intestinal function may be altered in decompensated chronic heart
failure (CHF) and translocating LPS may contribute to systemic inflammation observed in …

Current evidence about nutrition support in cardiac surgery patients—what do we know?

A Hill, E Nesterova, V Lomivorotov, S Efremov… - Nutrients, 2018 - mdpi.com
Nutrition support is increasingly recognized as a clinically relevant aspect of the intensive
care treatment of cardiac surgery patients. However, evidence from adequate large-scale …

Safe time limits of aortic cross-clamping and cardiopulmonary bypass in adult cardiac surgery

J Nissinen, F Biancari, JO Wistbacka, T Peltola… - …, 2009 - journals.sagepub.com
Objectives: We evaluated the impact of aortic cross-clamping time (XCT) and
cardiopulmonary bypass time (CPBT) on the immediate and late outcome after adult cardiac …

The relationship between inflammatory activation and clinical outcome after infant cardiopulmonary bypass

CK Allan, JW Newburger, E McGrath, J Elder… - Anesthesia & …, 2010 - journals.lww.com
BACKGROUND: Cardiopulmonary bypass (CPB) induces a systemic inflammatory
response. The magnitude and consequences in infants remain unclear. We assessed the …

[HTML][HTML] Postoperative complications and association with outcomes in pediatric cardiac surgery

HS Agarwal, KB Wolfram, BR Saville… - The Journal of thoracic …, 2014 - Elsevier
Objective Our primary aim was to study postoperative complications in pediatric cardiac
surgery patients and their association with cardiopulmonary bypass (CPB) use. The …

Magnitude of the inflammatory response to cardiopulmonary bypass and its relation to adverse clinical outcomes

JH Holmes Iv, NC Connolly, DL Paull, ME Hill… - Inflammation …, 2002 - Springer
Introduction: Cardiopulmonary bypass (CPB) induces an inflammatory response believed to
contribute to postoperative morbidity. We hypothesized that the magnitude of the …

Vitamin C to improve organ dysfunction in cardiac surgery patients—review and pragmatic approach

A Hill, S Wendt, C Benstoem, C Neubauer, P Meybohm… - Nutrients, 2018 - mdpi.com
The pleiotropic biochemical and antioxidant functions of vitamin C have sparked recent
interest in its application in intensive care. Vitamin C protects important organ systems …