Diabetes and tuberculosis

BI Restrepo - Understanding the host immune response against …, 2018 - Springer
The worldwide increase in the prevalence of diabetes has been most notable in TB-endemic
countries and has led to the re-emerging importance of the association between these two …

Influence of diabetes mellitus on immunity to human tuberculosis

P Kumar Nathella, S Babu - Immunology, 2017 - Wiley Online Library
Type 2 diabetes mellitus (DM) is a major risk factor for the development of active pulmonary
tuberculosis (TB), with development of DM pandemic in countries where TB is also endemic …

Systems immunology of diabetes-tuberculosis comorbidity reveals signatures of disease complications

CA Prada-Medina, KF Fukutani, N Pavan Kumar… - Scientific reports, 2017 - nature.com
Comorbid diabetes mellitus (DM) increases tuberculosis (TB) risk and adverse outcomes but
the pathological interactions between DM and TB remain incompletely understood. We …

Network-based analysis of comorbidities risk during an infection: SARS and HIV case studies

MA Moni, P Liò - BMC bioinformatics, 2014 - Springer
Background Infections are often associated to comorbidity that increases the risk of medical
conditions which can lead to further morbidity and mortality. SARS is a threat which is similar …

The interplay between systemic inflammation, oxidative stress, and tissue remodeling in tuberculosis

EP Amaral, CL Vinhaes… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Excessive and prolonged proinflammatory responses are associated with
oxidative stress, which is commonly observed during chronic tuberculosis (TB). Such …

Diabetes is associated with worse clinical presentation in tuberculosis patients from Brazil: a retrospective cohort study

L Gil-Santana, JL Almeida-Junior, CAM Oliveira… - PloS one, 2016 - journals.plos.org
Background The rising prevalence of diabetes mellitus (DM) worldwide, especially in
developing countries, and the persistence of tuberculosis (TB) as a major public health issue …

Diabetic nephropathy and gaseous modulators

SK Juin, R Ouseph, DD Gondim, VR Jala, U Sen - Antioxidants, 2023 - mdpi.com
Diabetic nephropathy (DN) remains the leading cause of vascular morbidity and mortality in
diabetes patients. Despite the progress in understanding the diabetic disease process and …

Immunologic, metabolic and genetic impact of diabetes on tuberculosis susceptibility

P Ssekamatte, OJ Sande, R Van Crevel… - Frontiers in …, 2023 - frontiersin.org
Due to the increasing prevalence of diabetes mellitus (DM) globally, the interaction between
DM and major global diseases like tuberculosis (TB) is of great public health significance …

Severe pulmonary radiological manifestations are associated with a distinct biochemical profile in blood of tuberculosis patients with dysglycemia

NN Barreda, MB Arriaga, JG Aliaga, K Lopez… - BMC Infectious …, 2020 - Springer
Background Diabetes mellitus (DM) is thought to affect tuberculosis (TB) clinical
presentation and treatment response. Whether DM impacts radiological manifestations of …

Associations between systemic inflammation, mycobacterial loads in sputum and radiological improvement after treatment initiation in pulmonary TB patients from …

EDD Mesquita, L Gil-Santana, D Ramalho… - BMC infectious …, 2016 - Springer
Background Mycobacterium tuberculosis infection is known to cause inflammation and lung
tissue damage in high-risk populations. Nevertheless, direct associations between …