Sepsis is expected to have a substantial impact on public health and cost as its prevalence
increases. Factors contributing to increased prevalence include a progressively aging …

Sepsis is the life-threatening organ dysfunction caused by a dysregulated host response to
infection and is the leading cause of death in intensive care units. Cardiac dysfunction …

Abstract Interleukin-6 (IL-6) plays a crucial role in host defense against infection and tissue
injuries and is a bioindicator of multiple distinct types of cytokine storms. In this review, we …

This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …

Background Sepsis and septic shock remain drivers for mortality in critically ill patients. The
heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality …

Importance Sepsis is a heterogeneous syndrome. Identification of distinct clinical
phenotypes may allow more precise therapy and improve care. Objective To derive sepsis …

Background After surgery, wound recovery in diabetic patients may be disrupted due to
delayed inflammation, which can lead to undesired consequences, and there is currently a …

Neutrophil extracellular traps (NETs) evolved to protect the host against microbial infections
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …

Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …

Background Timely interventions, such as antibiotics and intravenous fluids, have been
associated with reduced mortality in patients with sepsis. Artificial intelligence (AI) models …