[HTML][HTML] Immune mechanisms of pulmonary fibrosis with bleomycin

Y Ishida, Y Kuninaka, N Mukaida, T Kondo - International journal of …, 2023 - mdpi.com
Fibrosis and structural remodeling of the lung tissue can significantly impair lung function,
often with fatal consequences. The etiology of pulmonary fibrosis (PF) is diverse and …

The evolution of transcriptional regulation in eukaryotes

GA Wray, MW Hahn, E Abouheif… - Molecular biology …, 2003 - academic.oup.com
Gene expression is central to the genotype-phenotype relationship in all organisms, and it is
an important component of the genetic basis for evolutionary change in diverse aspects of …

[图书][B] Evolutionary parasitology: the integrated study of infections, immunology, ecology, and genetics

P Schmid-Hempel - 2021 - books.google.com
Parasites and infectious diseases are everywhere and represent some of the most potent
forces shaping the natural world. They affect almost every aspect imaginable in the life of …

[HTML][HTML] Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution

M Fumagalli, M Sironi, U Pozzoli… - PLoS …, 2011 - journals.plos.org
Previous genome-wide scans of positive natural selection in humans have identified a
number of non-neutrally evolving genes that play important roles in skin pigmentation …

From evolutionary genetics to human immunology: how selection shapes host defence genes

LB Barreiro, L Quintana-Murci - Nature Reviews Genetics, 2010 - nature.com
Pathogens have always been a major cause of human mortality, so they impose strong
selective pressure on the human genome. Data from population genetic studies, including …

[图书][B] Human evolutionary genetics: origins, peoples and disease

M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

Genetics of global gene expression

MV Rockman, L Kruglyak - Nature Reviews Genetics, 2006 - nature.com
A new field of genetic analysis of global gene expression has emerged in recent years,
driven by the realization that traditional techniques of linkage and association analysis can …

Implications of biogeography of human populations for'race'and medicine

SA Tishkoff, KK Kidd - Nature genetics, 2004 - nature.com
In this review, we focus on the biogeographical distribution of genetic variation and address
whether or not populations cluster according to the popular concept of'race'. We show that …

The application of molecular genetic approaches to the study of human evolution

LL Cavalli-Sforza, MW Feldman - Nature genetics, 2003 - nature.com
The past decade of advances in molecular genetic technology has heralded a new era for
all evolutionary studies, but especially the science of human evolution. Data on various …

Effects of inbreeding on the genetic diversity of populations

D Charlesworth - … Transactions of the Royal Society of …, 2003 - royalsocietypublishing.org
The study of variability within species is important to all biologists who use genetic markers.
Since the discovery of molecular variability among normal individuals, data have been …