PI3K/AKT/mTOR dysregulation and reprogramming metabolic pathways in renal cancer: Crosstalk with the VHL/HIF axis
Renal cell carcinoma (RCC) represents 85–95% of kidney cancers and is the most frequent
type of renal cancer in adult patients. It accounts for 3% of all cancer cases and is in 7th …
type of renal cancer in adult patients. It accounts for 3% of all cancer cases and is in 7th …
Using the synergy between HPLC-MS and MALDI-MS imaging to explore the lipidomics of clear cell renal cell carcinoma
L Martín-Saiz, B Abad-García, JD Solano-Iturri… - Analytical …, 2023 - ACS Publications
Lipid imaging mass spectrometry (LIMS) has been tested in several pathological contexts,
demonstrating its ability to segregate and isolate lipid signatures in complex tissues, thanks …
demonstrating its ability to segregate and isolate lipid signatures in complex tissues, thanks …
Lipids as Targets for Renal Cell Carcinoma Therapy
B Stepanovska Tanturovska, R Manaila… - International journal of …, 2023 - mdpi.com
Kidney cancer is among the top ten most common cancers to date. Within the kidney, renal
cell carcinoma (RCC) is the most common solid lesion occurring. While various risk factors …
cell carcinoma (RCC) is the most common solid lesion occurring. While various risk factors …
Unique sphingolipid signature identifies luminal and triple‐negative breast cancer subtypes
Breast cancer (luminal and triple‐negative breast cancer [TNBC]) is the most common
cancer among women in India and worldwide. Altered sphingolipid levels have emerged as …
cancer among women in India and worldwide. Altered sphingolipid levels have emerged as …
SCD5 regulation by VHL affects cell proliferation and lipid homeostasis in ccRCC
A Ganner, A Philipp, S Lagies, L Wingendorf, L Wang… - Cells, 2023 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal
cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of …
cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of …
Catfish Egg Lectin Enhances the Cytotoxicity of Sunitinib on Gb3-Expressing Renal Cancer Cells
J Ito, S Sugawara, T Tatsuta, M Hosono, M Sato - Biomedicines, 2023 - mdpi.com
Metastatic renal cell carcinoma (RCC) is not sufficiently responsive to anticancer drugs, and
thus, developing new drugs for advanced RCC remains vital. We previously reported that …
thus, developing new drugs for advanced RCC remains vital. We previously reported that …
An integrated strategy to explore the wine-processed mechanism of Corni Fructus on chronic renal failure based on metabolomics, network analysis and …
S Sun, X Jia, M Yang, N Wang, Q Zhang… - Journal of Pharmacy …, 2023 - academic.oup.com
Abstract Objectives Corni Fructus is one of the most famous traditional Chinese medicines
(TCMs) for the treatment of various chronic kidney diseases. Wine-processed Corni Fructus …
(TCMs) for the treatment of various chronic kidney diseases. Wine-processed Corni Fructus …
Integrative analysis of bulk and single‐cell RNA sequencing reveals sphingolipid metabolism and immune landscape in clear cell renal cell carcinoma
D Xie, Z Han, Y Wang, H Shi, X Wu, J Wu… - Environmental … - Wiley Online Library
Clear cell renal cell carcinoma (ccRCC) is characterized by its aggressive behavior and
complex molecular heterogeneity, posing significant challenges for treatment and …
complex molecular heterogeneity, posing significant challenges for treatment and …
[PDF][PDF] SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC. Cells 2023, 12, 835
A Ganner, A Philipp, S Lagies, L Wingendorf, L Wang… - 2023 - pdfs.semanticscholar.org
Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal
cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of …
cancer, and inactivation of the VHL tumor suppressor gene is found in almost all cases of …