Since the days of Ramón y Cajal, the vast diversity of neuronal and particularly dendrite
morphology has been used to catalog neurons into different classes. Dendrite morphology …

Axon regeneration in response to injury has been documented in many animals over
several hundred years. In contrast, how neurons respond to dendrite injury has been …

Unlike many cell types, neurons are not typically replaced if damaged. Therefore,
regeneration of damaged cellular domains is critical for maintenance of neuronal function …

Dendrites play irreplaceable roles in the nerve conduction pathway and are vulnerable to
various insults. Peripheral axotomy of motor neurons results in the retraction of dendritic …

Axon and dendrite development require the cooperation of actin and microtubule
cytoskeletons. Microtubules form a well-organized network to direct polarized trafficking and …

Most neurons are not replaced after injury and thus possess robust intrinsic mechanisms for
repair after damage. Axon injury triggers a calcium wave, and calcium and cAMP can …

The C. elegans hermaphrodite distal tip cell (DTC) leads gonadogenesis. Loss-of-function
mutations in a C. elegans ortholog of the Rac1 GTPase (ced-10) and its GEF complex (ced …

PVD neuron of C. elegans has become an attractive model for the study of dendrite
development and regeneration due to its elaborate and stereotype dendrite morphology …

PVD neuron of Caenorhabditis elegans is a highly polarized cell with well-defined axonal,
and dendritic compartments. PVD neuron operates in multiple sensory modalities including …

Promoting axonal regeneration is an effective strategy for recovery from traumatic spinal
cord injury (SCI). Spastin, a microtubule-severing protein, modulates axonal outgrowth and …