Virus-mediated cell-cell fusion
Cell-cell fusion between eukaryotic cells is a general process involved in many
physiological and pathological conditions, including infections by bacteria, parasites, and …
physiological and pathological conditions, including infections by bacteria, parasites, and …
Pathogenesis of human immunodeficiency virus infection
JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …
number of different cells in the body and escaping the host immune response against it. HIV …
The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
We examined the ability of chemokine receptors and related G protein–coupled receptors to
facilitate infection by primary, clinical HIV-1 isolates. CCR5, when expressed along with …
facilitate infection by primary, clinical HIV-1 isolates. CCR5, when expressed along with …
Mechanisms for cell-to-cell transmission of HIV-1
While HIV-1 infection of target cells with cell-free viral particles has been largely
documented, intercellular transmission through direct cell-to-cell contact may be a …
documented, intercellular transmission through direct cell-to-cell contact may be a …
Macrophages and their relevance in Human Immunodeficiency Virus Type I infection
H Koppensteiner, R Brack-Werner, M Schindler - Retrovirology, 2012 - Springer
Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …
HIV‐1 replication is controlled at the level of T cell activation and proviral integration.
M Stevenson, TL Stanwick, MP Dempsey… - The EMBO …, 1990 - embopress.org
During progression of the Acquired Immune Deficiency Syndrome (AIDS), the human
immunodeficiency virus type 1 (HIV‐1) is harbored in CD4+ T cells, which act as the primary …
immunodeficiency virus type 1 (HIV‐1) is harbored in CD4+ T cells, which act as the primary …
Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation
Z Qian, SR Dominguez, KV Holmes - PloS one, 2013 - journals.plos.org
Little is known about the biology of the emerging human group c betacoronavirus, Middle
East Respiratory Syndrome coronavirus (MERS-CoV). Because coronavirus spike …
East Respiratory Syndrome coronavirus (MERS-CoV). Because coronavirus spike …
The human immunodeficiency virus: infectivity and mechanisms of pathogenesis
AS Fauci - Science, 1988 - science.org
Infection with the human immunodeficiency virus (HIV) results in a profound
immunosuppression due predominantly to a selective depletion of helper/inducer T …
immunosuppression due predominantly to a selective depletion of helper/inducer T …
HIV-1 pathogenesis
M Stevenson - Nature medicine, 2003 - nature.com
Despite considerable advances in HIV science in the past 20 years, the reason why HIV-1
infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains …
infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains …
Dendritic Cells Exposed to Human Immunodeficiency Virus Type-1 Transmit a Vigorous Cytopathic Infection to CD4+ T Cells
PU Cameron, PS Freudenthal, JM Barker, S Gezelter… - Science, 1992 - science.org
The paucity of virus-laden CD4+ cells in individuals infected with human immunodeficiency
virus type-1 (HIV-1) contrasts with the greatly reduced numbers and function of these …
virus type-1 (HIV-1) contrasts with the greatly reduced numbers and function of these …