Nanoparticle science is rapidly changing the landscape of various scientific fields and
defining new technological platforms. This is perhaps even more evident in the field of …

Clathrin-mediated endocytosis is a key process in vesicular trafficking that transports a wide
range of cargo molecules from the cell surface to the interior. Clathrin-mediated endocytosis …

Nucleotide-binding, leucine-rich repeat receptors (NLRs) are major immune receptors in
plants and animals. Upon activation, the Arabidopsis NLR protein ZAR1 forms a pentameric …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry starts with
membrane attachment and ends with spike (S) protein–catalyzed membrane fusion …

Curved membranes are key features of intracellular organelles, and their generation
involves dynamic protein complexes. Here we describe the fundamental mechanisms such …

Clathrin-mediated endocytosis (CME) is the major endocytic pathway in mammalian cells. It
is responsible for the uptake of transmembrane receptors and transporters, for remodeling …

Virus entry is a multistep process. It initiates when the virus attaches to the host cell and
ends when the viral contents reach the cytosol. Genetically unrelated viruses can subvert …

Collaborative efforts from the fields of biology, materials science, and engineering are
leading to exciting progress in the development of nanomedicines. Since the targets of many …

Of the approximately 70 human Rab GTPases, nearly three-quarters are involved in
endocytic trafficking. Significant plasticity in endosomal membrane transport pathways is …

To sustain neurotransmission, synaptic vesicles and their associated proteins must be
recycled locally at synapses. Synaptic vesicles are thought to be regenerated approximately …