Genetic Signature of Human Pancreatic Cancer and Personalized Targeting

SJ Reshkin, RA Cardone, T Koltai - Cells, 2024 - mdpi.com
Pancreatic cancer is a highly lethal disease with a 5-year survival rate of around 11–12%.
Surgery, being the treatment of choice, is only possible in 20% of symptomatic patients. The …

Redefining precision in cancer treatment: a novel electrochemical approach using bimetal oxide composites for Niraparib quantification

MH Yıldır, G Kurtay, W Bouali, AA Genç, N Erk - Microchemical Journal, 2024 - Elsevier
Amidst the accelerating global surge in cancer incidences, there has been a parallel
increase in worldwide efforts to propel the development of advanced therapeutic agents …

Atherosclerosis is a smooth muscle cell–driven tumor-like disease

H Pan, SE Ho, C Xue, J Cui, QS Johanson, N Sachs… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Atherosclerosis, a leading cause of cardiovascular disease, involves the
pathological activation of various cell types, including immunocytes (eg, macrophages and T …

Claudin-4 modulates autophagy via SLC1A5/LAT1 as a tolerance mechanism for genomic instability in ovarian cancer

FR Villagomez, J Lang, P Webb, M Neville… - bioRxiv, 2024 - biorxiv.org
Genome instability is key for tumor heterogeneity and derives from defects in cell division
and DNA damage repair. Tumors show tolerance for this characteristic, but its accumulation …