Nitric oxide: clinical applications in critically ill patients

S Redaelli, A Magliocca, R Malhotra, G Ristagno… - Nitric Oxide, 2022 - Elsevier
Inhaled nitric oxide (iNO) acts as a selective pulmonary vasodilator and it is currently
approved by the FDA for the treatment of persistent pulmonary hypertension of the newborn …

Personalized respiratory support in ARDS: a physiology-to-bedside review

SL Cutuli, DL Grieco, T Michi, M Cesarano… - Journal of Clinical …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a leading cause of disability and mortality
worldwide, and while no specific etiologic interventions have been shown to improve …

[HTML][HTML] Inhaled pulmonary vasodilators: a narrative review

K Liu, H Wang, SJ Yu, GW Tu, Z Luo - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Pulmonary hypertension (PH) is a severe disease that affects people of all ages. It can occur
as an idiopathic disorder at birth or as part of a variety of cardiovascular and pulmonary …

Nitric oxide in cardiac surgery: a review article

NO Kamenshchikov, N Duong, L Berra - Biomedicines, 2023 - mdpi.com
Perioperative organ injury remains a medical, social and economic problem in cardiac
surgery. Patients with postoperative organ dysfunction have increases in morbidity, length of …

Management of challenging cardiopulmonary bypass separation

F Monaco, AL Di Prima, JH Kim, MJ Plamondon… - Journal of cardiothoracic …, 2020 - Elsevier
SEPARATION from cardiopulmonary bypass (CPB) after cardiac surgery is a progressive
transition from full mechanical circulatory and respiratory support to spontaneous …

[HTML][HTML] Pulmonary vasodilator and inodilator drugs in cardiac surgery: a systematic review with Bayesian network meta-analysis

S Sardo, VF Tripodi, F Guerzoni, M Musu… - Journal of cardiothoracic …, 2023 - Elsevier
Objective. We performed a systematic review to evaluate the effect of pharmacological
therapy of pulmonary hypertension in the perioperative setting of elective cardiac surgery …

Inhaled nitric oxide: can it serve as a savior for COVID-19 and related respiratory and cardiovascular diseases?

Y Zhao, C Li, S Zhang, J Cheng, Y Liu, X Han… - Frontiers in …, 2023 - frontiersin.org
Nitric oxide (NO), as an important gaseous medium, plays a pivotal role in the human body,
such as maintaining vascular homeostasis, regulating immune-inflammatory responses …

Management of postoperative hypoxemia

K Liu, JB Scott, G Jing, J Li - Respiratory Care, 2021 - rc.rcjournal.com
Hypoxemia is common in postoperative patients and is associated with prolonged hospital
stays, high costs, and increased mortality. This review discusses the postoperative …

Inhaled nitric oxide treatment for aneurysmal SAH patients with delayed cerebral ischemia

C Fung, WJ Z'Graggen, SM Jakob, J Gralla… - Frontiers in …, 2022 - frontiersin.org
Background We demonstrated experimentally that inhaled nitric oxide (iNO) dilates
hypoperfused arterioles, increases tissue perfusion, and improves neurological outcome …

Effect of nitric oxide on postoperative acute kidney injury in patients who underwent cardiopulmonary bypass: a systematic review and meta-analysis with trial …

J Hu, S Spina, F Zadek, NO Kamenshchikov… - Annals of Intensive …, 2019 - Springer
Background The effect of nitric oxide (NO) on renal function is controversial in critical illness.
We performed a systematic meta-analysis and trial sequential analysis to determine the …