Puromycin is a naturally occurring aminonucleoside antibiotic that inhibits protein synthesis
by ribosome-catalyzed incorporation into the C-terminus of elongating nascent chains …

Highlights•∼ 2550 mRNA species are localized in dendrites and/or axons.•The alternative
usage of 3′ UTR isoforms dictates the fate of an mRNA molecule.•Novel multiplexed FISH …

Inhibition of protein biosynthesis is a promising strategy to develop new therapeutic
modalities for cancers; however, noninvasive precise regulation of this cellular event in …

Photocaging facilitates non‐invasive and precise spatio‐temporal control over the release of
biologically relevant small‐and macro‐molecules using light. However, sub‐cellular …

Protein synthesis stands at the last stage of the central dogma of molecular biology,
providing a final regulatory layer for gene expression. Reacting to environmental cues and …

Photocages enable the precise activation of molecular function with light in many research
fields, such as anticancer treatment, where remote spatiotemporal control over the release of …

Emerging evidence indicates that protein synthesis and degradation are necessary for the
remodeling of synapses. These two processes govern cellular protein turnover, are tightly …

Photocleavable protecting groups (PPGs) play a pivotal role in numerous studies. They
enable controlled release of small effector molecules to induce biochemical function. The …

Hydrogen peroxide (H2O2) is a central reactive oxygen species (ROS) that contributes to
diseases from obesity to cancer to neurodegeneration but is also emerging as an important …

Translation is an elementary cellular process that involves a large number of factors
interacting in a concerted fashion with the ribosome. Numerous natural products have …