Epithelioid sarcoma—from genetics to clinical practice
AM Czarnecka, P Sobczuk, M Kostrzanowski, M Spalek… - Cancers, 2020 - mdpi.com
Epithelioid sarcoma is a mesenchymal soft tissue sarcoma often arising in the extremities,
usually in young adults with a pick of incidence at 35 years of age. Epithelioid sarcoma (ES) …
usually in young adults with a pick of incidence at 35 years of age. Epithelioid sarcoma (ES) …
Beyond SMARCB1 loss: recent insights into the pathobiology of epithelioid sarcoma
E Del Savio, R Maestro - Cells, 2022 - mdpi.com
Epithelioid sarcoma (ES) is a very rare and aggressive mesenchymal tumor of unclear origin
and uncertain lineage characterized by a prevalent epithelioid morphology. The only …
and uncertain lineage characterized by a prevalent epithelioid morphology. The only …
Epithelioid sarcoma: opportunities for biology-driven targeted therapy
Epithelioid sarcoma (ES) is a soft tissue sarcoma of children and young adults for which the
preferred treatment for localized disease is wide surgical resection. Medical management is …
preferred treatment for localized disease is wide surgical resection. Medical management is …
New therapeutic targets in soft tissue sarcoma
EG Demicco, RG Maki, DC Lev… - Advances in anatomic …, 2012 - journals.lww.com
Soft tissue sarcomas are an uncommon and diverse group of more than 50 mesenchymal
malignancies. The pathogenesis of many of these is poorly understood, but others have …
malignancies. The pathogenesis of many of these is poorly understood, but others have …
Pharmacotherapeutic strategies for epithelioid sarcoma: are we any closer to a non-surgical cure?
M Meissner, A Napolitano, K Thway… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Epithelioid sarcoma (ES) is a rare soft tissue sarcoma subtype, predominantly
occurring in children and young adults. Despite optimal management of localized disease …
occurring in children and young adults. Despite optimal management of localized disease …
Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma
X Xie, MPH Ghadimi, ED Young, R Belousov… - Clinical Cancer …, 2011 - AACR
Purpose: Molecular deregulations underlying epithelioid sarcoma (ES) progression are
poorly understood yet critically needed to develop new therapies. Epidermal growth factor …
poorly understood yet critically needed to develop new therapies. Epidermal growth factor …
Candidate biomarkers for specific intraoperative near-infrared imaging of soft tissue sarcomas: a systematic review
Z Rijs, AN Shifai, SE Bosma, PJK Kuppen… - Cancers, 2021 - mdpi.com
Simple Summary Near-infrared imaging of tumors during surgery facilitates the oncologic
surgeon to distinguish malignant from healthy tissue. The technique is based on fluorescent …
surgeon to distinguish malignant from healthy tissue. The technique is based on fluorescent …
Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation
AC Harttrampf, MEM da Costa, A Renoult… - BMC cancer, 2021 - Springer
Background Epithelioid sarcomas and rhabdoid tumors are rare, aggressive malignancies
with poor prognosis. Both are characterized by INI1 alterations and deregulation of growth …
with poor prognosis. Both are characterized by INI1 alterations and deregulation of growth …
[HTML][HTML] Photoimmunotheranostics of epithelioid sarcoma by targeting CD44 or EGFR
Epithelioid sarcoma (ES) is a rare soft tissue neoplasm with high recurrence rates. Wide
surgical resection remains the only potential curative treatment. ES presents most commonly …
surgical resection remains the only potential curative treatment. ES presents most commonly …
[HTML][HTML] The evolving management of epithelioid sarcoma
A Alves, A Constantinidou, K Thway… - European Journal of …, 2021 - ncbi.nlm.nih.gov
Epithelioid sarcoma (ES) is an aggressive malignant soft-tissue tumour which was first
named in the 1970s by Franz Enzinger (Enzinger, 1970). ES is rare, accounting for less than …
named in the 1970s by Franz Enzinger (Enzinger, 1970). ES is rare, accounting for less than …