The title to a seminar presentation by IC Gunsalus in 1973 was “Oxygen: An essential toxin”,
referring to the complex role that atmospheric dioxygen has in biology. The relatively simple …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

The 6th edition of this classic comprises the most comprehensive guide to infrared and
Raman spectra of inorganic, organometallic, bioinorganic, and coordination compounds …

In order to fully understand how a catalytic system operates, it is necessary to establish the
structure of the functional unit as well as to determine the changes that the catalytic center …

This book covers the relevant aspects of cytochromes P450 for understanding their structure,
function and mechanisms of action, such as physicochemical characterization methods …

An overview of the application of Fourier transform infrared spectroscopy for the analysis of
the structure of proteins and protein–ligand recognition is given. The principle of the …

Cytochromes P450 constitute a broad class of heme monooxygenase enzymes with more
than 11,500 isozymes which have been identified in organisms from all biological kingdoms …

Page 1 Cytochromes P450 Structure, Function and Mechanism David FV Lewis Also
available as a printed book see title verso for ISBN details Page 2 Cytochromes P450 …

The kinetics of formation and breakdown of the putative active oxygenating intermediate in
cytochrome P450, a ferryl-oxo-(π) porphyrin cation radical (Compound I), have been …

The gaseous XO molecules (X= C, N or O) bind to the heme prosthetic group of heme
proteins, and thereby activate or inhibit key biological processes. These events depend on …