[HTML][HTML] Monocyte programming by cancer therapy

M Patysheva, A Frolova, I Larionova… - Frontiers in …, 2022 - frontiersin.org
Monocytes in peripheral blood circulation are the precursor of essential cells that control
tumor progression, that include tumor-associated macrophages (TAMs), dendritic cells …

[HTML][HTML] Macrophage and neutrophil interactions in the pancreatic tumor microenvironment drive the pathogenesis of pancreatic cancer

HG Pratt, KJ Steinberger, NE Mihalik, S Ott, T Whalley… - Cancers, 2021 - mdpi.com
Simple Summary The survival rates for patients with pancreatic adenocarcinoma are very
low. This dismal prognosis is due in part to late detection and early development of …

[HTML][HTML] Tumor cell-derived exosomes deliver TIE2 protein to macrophages to promote angiogenesis in cervical cancer

S Du, J Qian, S Tan, W Li, P Liu, J Zhao, Y Zeng, L Xu… - Cancer letters, 2022 - Elsevier
Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 2
(TIE2)-expressing macrophages (TEMs) are an angiogenesis-promoting subset of tumor …

[HTML][HTML] The underexplored landscape of hypoxia-inducible factor 2 alpha and potential roles in tumor macrophages: a review

KJ Steinberger, TD Eubank - Oxygen, 2023 - mdpi.com
Low tissue oxygenation, termed hypoxia, is a characteristic of solid tumors with negative
consequences. Tumor-associated macrophages (TAMs) accumulate in hypoxic tumor …

Benzothiazole derivatives in the design of antitumor agents

N Paoletti, CT Supuran - Archiv der Pharmazie, 2024 - Wiley Online Library
Benzothiazoles are a class of heterocycles with multiple applications as anticancer,
antibiotic, antiviral, and anti‐inflammatory agents. Benzothiazole is a privileged scaffold in …

[HTML][HTML] Roles of Tumor-Associated Macrophages in Tumor Environment and Strategies for Targeting Therapy

MQ Liu, JW Zhang, JW Zhu - Pharmaceutical Fronts, 2023 - thieme-connect.com
Tumor-associated macrophages (TAMs) constitute a significant component of the tumor
microenvironment. This work reviewed the latest progress in comprehending the function of …

人类肿瘤中Tie2 阳性单核巨噬细胞研究进展

江楚怡, 蔡晶, 王泽华, 陈媛媛 - 肿瘤防治研究, 2021 - zlfzyj.com
Tie2 阳性单核巨噬细胞(TEMs) 是一类表达酪氨酸激酶受体Tie2 的单核细胞或巨噬细胞,
在人类和鼠类中均有发现, 可存在于外周血和组织中, 参与肿瘤血管生成, 淋巴管生成和免疫抑制 …

[HTML][HTML] Modified microvessel density based on perfusion distance: a preferable NSCLC prognostic factor

Y Tong, D Yang, X Mi, Y Song, W Xin… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Despite the vital role of blood perfusion in tumor progression, the prognostic
value of typical blood perfusion markers, such as microvessel density (MVD) or microvessel …

[PDF][PDF] A hypoxia-related gene pairs signature for predicting overall survival in lung adenocarcinoma

K Li, B Zhang - 2021 - scholar.archive.org
Background: Increasing evidence has depicted the clinical importance of the correlation
between hypoxia and immune status in lung adenocarcinoma environment (LUAD) …