Inflammation and oxidative stress conditions lead to a variety of oxidative modifications of
lipoprotein phospholipids implicated in the occurrence and development of atherosclerotic …

Due to their unique chemical structure, plasmalogens do not only exhibit distinct biophysical
and biochemical features, but require specialized pathways of biosynthesis and …

Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we
reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls intracellular …

Conspectus Water-soluble proteins as well as membrane-bound proteins associate with
membrane surfaces and bind specific lipid molecules in specific sites on the protein …

Occludin (OCLN) is a tight junction protein and Ocln deletion mutation causes male infertility
in mice. However, the role of OCLN in male reproductive system remains unknown. In this …

Ferroptosis is a regulated form of cell death, the mechanism of which is still to be
understood. 15-lipoxygenase (15LOX) complex with phosphatidylethanolamine (PE) …

Ischemic stroke, which occurs following blockage of the blood supply to the brain, is a
leading cause of death worldwide. Its main cause is atherosclerosis, a disease of the …

Defining optimal nutrition in animals and humans remains a main scientific challenge. The
objective of the work was to develop a dynamic model of reactive oxygen species (ROS) …

Ceramide transfer protein CERT is the mediator of nonvesicular transfer of ceramide from
the ER to Golgi. In CERT, START is the domain responsible for the binding and transport of …

Recruitment of enzymes to intracellular membranes often modulates their catalytic activity,
which can be important in cell signaling and membrane trafficking. Thus, re-localization is …