[HTML][HTML] Heterogeneity of the head and neck squamous cell carcinoma immune landscape and its impact on immunotherapy

M Canning, G Guo, M Yu, C Myint… - Frontiers in cell and …, 2019 - frontiersin.org
Head and neck squamous cell carcinomas (HNSCCs) are highly aggressive, multi-factorial
tumors in the upper aerodigestive tract affecting more than half a million patients worldwide …

[HTML][HTML] Recent advances and future directions in clinical management of head and neck squamous cell carcinoma

J Muzaffar, S Bari, K Kirtane, CH Chung - Cancers, 2021 - mdpi.com
Simple Summary Even with recent advances, there are urgent needs for novel therapies to
improve overall survival and decrease toxicities in the management of head and neck …

[HTML][HTML] The head and neck cancer immune landscape and its immunotherapeutic implications

R Mandal, Y Şenbabaoğlu, A Desrichard, JJ Havel… - JCI insight, 2016 - ncbi.nlm.nih.gov
Recent clinical trials have demonstrated a clear survival advantage in advanced head and
neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade …

[HTML][HTML] Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis

JL Roh, EH Kim, H Jang, D Shin - Redox biology, 2017 - Elsevier
Artesunate, an anti-malarial drug, has been repurposed as an anticancer drug due to its
induction of cell death via reactive oxygen species (ROS) production. However, the …

Diagnosis, removal, or mechanical damaging of tumor using plasmonic nanobubbles

DO Lapotko, K Hleb - US Patent 10,471,159, 2019 - Google Patents
Processes of intraoperative diagnosis and elimination of tumors or micro-tumors or cancer
cells or tumor micro environment (TME) with plasmonic nanobubbles (PNBS) are disclosed …

[HTML][HTML] Oral microbiota community dynamics associated with oral squamous cell carcinoma staging

CY Yang, YM Yeh, HY Yu, CY Chin, CW Hsu… - Frontiers in …, 2018 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a highly aggressive cancer and the fourth leading
malignancy among males in Taiwan. Some pathogenic bacteria are associated with …

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

N Agrawal, MJ Frederick, CR Pickering, C Bettegowda… - Science, 2011 - science.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide. To explore the genetic origins of this cancer, we used whole-exome sequencing …

Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced …

R Haddad, A O'Neill, G Rabinowits, R Tishler… - The Lancet …, 2013 - thelancet.com
Background The relative efficacy of the addition of induction chemotherapy to
chemoradiotherapy compared with chemoradiotherapy alone for patients with head and …

Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

JL Roh, EH Kim, HJ Jang, JY Park, D Shin - Cancer letters, 2016 - Elsevier
Inhibition of key molecules related to ferroptosis, cystine/glutamate antiporter and
glutathione peroxidase, may induce eradication of chemotherapy/radiotherapy-resistant …

[PDF][PDF] Targeting BMI1+ cancer stem cells overcomes chemoresistance and inhibits metastases in squamous cell carcinoma

D Chen, M Wu, Y Li, I Chang, Q Yuan… - Cell stem cell, 2017 - cell.com
Squamous cell carcinoma in the head and neck (HNSCC) is a common yet poorly
understood cancer, with adverse clinical outcomes due to treatment resistance, recurrence …