Oncolytic virus delivery modulated immune responses toward cancer therapy: Challenges and perspectives

M Keshavarz, SM Miri, E Behboudi, Y Arjeini… - International …, 2022 - Elsevier
Oncolytic viruses (OVs) harness the hallmarks of tumor cells and cancer-related immune
responses for the lysis of malignant cells, modulation of the tumor microenvironment, and …

[HTML][HTML] Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity

J Lin, S Sun, K Zhao, F Gao, R Wang, Q Li… - Nature …, 2023 - nature.com
The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly
killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis …

[HTML][HTML] Pathologic mechanisms of the Newcastle disease virus

D Zhang, Z Ding, X Xu - Viruses, 2023 - mdpi.com
Newcastle disease (ND) has been a consistent risk factor to the poultry industry worldwide.
Its pathogen, Newcastle disease virus (NDV), is also a promising antitumor treatment …

Oncolytic viruses improve cancer immunotherapy by reprogramming solid tumor microenvironment

L Zhang, SA Pakmehr, R Shahhosseini, M Hariri… - Medical Oncology, 2023 - Springer
Immunotherapies using immune checkpoint inhibitors (ICIs) and chimeric antigen receptor
(CAR) T-cell therapy have achieved successful results against several types of human …

[HTML][HTML] Combination immunotherapy using oncolytic virus for the treatment of advanced solid tumors

CM Oh, HJ Chon, C Kim - International journal of molecular sciences, 2020 - mdpi.com
Oncolytic virus (OV) is a new therapeutic strategy for cancer treatment. OVs can selectively
infect and destroy cancer cells, and therefore act as an in situ cancer vaccine by releasing …

[HTML][HTML] Immune landscape and immunotherapy options in cervical carcinoma

K Kousar, T Ahmad, F Naseer, S Kakar, S Anjum - Cancers, 2022 - mdpi.com
Simple Summary Cervical cancer is one of the most common cancers with a high mortality
rate, especially in women of reproductive age. A lot of treatment modalities are being used in …

[HTML][HTML] Therapeutic potential of oncolytic viruses in the era of precision oncology

M Kingsak, T Meethong, J Jongkhumkrong… - Biomaterials …, 2023 - ncbi.nlm.nih.gov
Oncolytic virus (OV) therapy has been shown to be an effective targeted cancer therapy
treatment in recent years, providing an avenue of treatment that poses no damage to …

[HTML][HTML] Developing oncolytic viruses for the treatment of cervical cancer

E Kalafati, E Drakopoulou, NP Anagnou, KI Pappa - Cells, 2023 - mdpi.com
Cervical cancer represents one of the most important malignancies among women
worldwide. Current therapeutic approaches for cervical cancer are reported not only to be …

[HTML][HTML] A bibliometric review of oncolytic virus research as a novel approach for cancer therapy

AS Mozaffari Nejad, T Noor, ZH Munim, MY Alikhani… - Virology Journal, 2021 - Springer
Background In recent years, oncolytic viruses (OVs) have drawn attention as a novel therapy
to various types of cancers, both in clinical and preclinical cancer studies all around the …

Reprogramming the tumor microenvironment to improve the efficacy of cancer immunotherapies

JA Faraj, AJH Al-Athari, SED Mohie, IK Kadhim… - Medical Oncology, 2022 - Springer
The immunotherapeutic approaches based on checkpoint inhibitors, tumor vaccination,
immune cell-based therapy, and cytokines were developed to engage the patient's immune …