[HTML][HTML] Post-acute COVID-19 syndrome

A Nalbandian, K Sehgal, A Gupta, MV Madhavan… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …

The SARS-CoV-2 as an instrumental trigger of autoimmunity

A Dotan, S Muller, D Kanduc, P David, G Halpert… - Autoimmunity …, 2021 - Elsevier
Autoimmunity may be generated by a variety of factors by creating a hyper-stimulated state
of the immune system. It had been established long ago that viruses are a substantial …

Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches

Y Jin, W Ji, H Yang, S Chen, W Zhang… - Signal transduction and …, 2020 - nature.com
On 12 March 2020, the outbreak of coronavirus disease 2019 (COVID-19) was declared a
pandemic by the World Health Organization. As of 4 August 2020, more than 18 million …

Thrombosis in COVID‐19

TC Hanff, AM Mohareb, J Giri, JB Cohen… - American journal of …, 2020 - Wiley Online Library
Thrombotic complications are frequent in COVID‐19 and contribute significantly to mortality
and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be …

Epidemiology and organ specific sequelae of post-acute COVID19: a narrative review

E Korompoki, M Gavriatopoulou, RS Hicklen… - Journal of Infection, 2021 - Elsevier
Objectives “Long COVID”, a term coined by COVID-19 survivors, describes persistent or new
symptoms in a subset of patients who have recovered from acute illness. Globally, the …

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

DC Mastellos, BGPP da Silva, BAL Fonseca… - Clinical …, 2020 - Elsevier
Growing clinical evidence has implicated complement as a pivotal driver of COVID-19
immunopathology. Deregulated complement activation may fuel cytokine-driven hyper …

Pathophysiology of Post-COVID syndromes: a new perspective

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb, NN Welson - Virology Journal, 2022 - Springer
Most COVID-19 patients recovered with low mortality; however, some patients experienced
long-term symptoms described as “long-COVID” or “Post-COVID syndrome”(PCS). Patients …

Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms

E Song, CM Bartley, RD Chow, TT Ngo, R Jiang… - Cell Reports …, 2021 - cell.com
Individuals with coronavirus disease 2019 (COVID-19) frequently develop neurological
symptoms, but the biological underpinnings of these phenomena are unknown. Through …

COVID-19 vasculitis and novel vasculitis mimics

D McGonagle, C Bridgewood, AV Ramanan… - The Lancet …, 2021 - thelancet.com
COVID-19 has been occasionally linked to histologically confirmed cutaneous vasculitis and
a Kawasaki-like vasculitis, with these entities generally having minimal or no lung …

Beyond the clot: perfusion imaging of the pulmonary vasculature after COVID-19

RT Dhawan, D Gopalan, L Howard… - The Lancet …, 2021 - thelancet.com
A compelling body of evidence points to pulmonary thrombosis and thromboembolism as a
key feature of COVID-19. As the pandemic spread across the globe over the past few …