Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

[HTML][HTML] On the structure of dynamic principal component analysis used in statistical process monitoring

E Vanhatalo, M Kulahci, B Bergquist - Chemometrics and intelligent …, 2017 - Elsevier
When principal component analysis (PCA) is used for statistical process monitoring it relies
on the assumption that data are time independent. However, industrial data will often exhibit …

Sub-millimetre DOI detector based on monolithic LYSO and digital SiPM for a dedicated small-animal PET system

R Marcinkowski, P Mollet, R Van Holen… - Physics in Medicine …, 2016 - iopscience.iop.org
The mouse model is widely used in a vast range of biomedical and preclinical studies.
Thanks to the ability to detect and quantify biological processes at the molecular level in …

Artificial neural networks for positioning of gamma interactions in monolithic PET detectors

M Decuyper, M Stockhoff… - Physics in Medicine …, 2021 - iopscience.iop.org
To detect gamma rays with good spatial, timing and energy resolution while maintaining
high sensitivity we need accurate and efficient algorithms to estimate the first gamma …

Optical simulation study on the spatial resolution of a thick monolithic PET detector

M Stockhoff, R Van Holen… - Physics in Medicine & …, 2019 - iopscience.iop.org
The intrinsic spatial resolution of clinical positron emission tomography (PET) detectors is~ 3–
4 mm. A further improvement of the resolution using pixelated detectors will not only result in …

Novel preclinical PET geometrical concept using a monolithic scintillator crystal offering concurrent enhancement in spatial resolution and detection sensitivity: a …

A Sanaat, H Arabi, MR Ay, H Zaidi - Physics in Medicine & …, 2020 - iopscience.iop.org
We propose a small-animal PET scanner design combining two sets of monolithic crystals
with two different thicknesses. The detectors with thinner crystals serve for high resolution …

Experimental Validation of an Efficient Fan-Beam Calibration Procedure for -Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors

G Borghi, V Tabacchini, S Seifert… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence
resolving time. However, their practical use for positron emission tomography (PET) and …

Deep residual-convolutional neural networks for event positioning in a monolithic annular PET scanner

G Jaliparthi, PF Martone, AV Stolin… - Physics in Medicine & …, 2021 - iopscience.iop.org
PET scanners based on monolithic pieces of scintillator can potentially produce superior
performance characteristics (high spatial resolution and detection sensitivity, for example) …

Performance of long rectangular semi‐monolithic scintillator PET detectors

X Zhang, X Wang, N Ren, B Hu, B Ding… - Medical …, 2019 - Wiley Online Library
Purpose High‐sensitivity and high‐resolution depth‐encoding positron emission
tomography (PET) detectors are required to simultaneously improve the sensitivity and …

Novel method to measure the intrinsic spatial resolution in PET detectors based on monolithic crystals

A González-Montoro, F Sanchez, P Bruyndonckx… - Nuclear Instruments and …, 2019 - Elsevier
The main aim of this work is to provide a method to retrieve the intrinsic spatial resolution of
a gamma-ray detector block based on monolithic crystals within an assembled scanner. This …