Lyme disease pathogenesis
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
[HTML][HTML] Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …
burgdorferi, has risen from relative obscurity to become a global public health problem and a …
Prophages and bacterial genomics: what have we learned so far?
S Casjens - Molecular microbiology, 2003 - Wiley Online Library
Epigraph There is something fascinating about science. One gets such wholesale returns of
conjecture out of such a trifling investment of fact. Mark Twain 1883 Life on the Mississippi …
conjecture out of such a trifling investment of fact. Mark Twain 1883 Life on the Mississippi …
Diagnosis of Lyme borreliosis
ME Aguero-Rosenfeld, G Wang… - Clinical microbiology …, 2005 - Am Soc Microbiol
SUMMARY A large amount of knowledge has been acquired since the original descriptions
of Lyme borreliosis (LB) and of its causative agent, Borrelia burgdorferi sensu stricto. The …
of Lyme borreliosis (LB) and of its causative agent, Borrelia burgdorferi sensu stricto. The …
Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals
D Grimm, K Tilly, R Byram, PE Stewart… - Proceedings of the …, 2004 - National Acad Sciences
Environmentally responsive synthesis of surface proteins represents a hallmark of the
infectious cycle of the Lyme disease agent, Borrelia burgdorferi. Here we created and …
infectious cycle of the Lyme disease agent, Borrelia burgdorferi. Here we created and …
Biology of infection with Borrelia burgdorferi
K Tilly, PA Rosa, PE Stewart - Infectious disease clinics of North America, 2008 - Elsevier
The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir
is a variety of small mammals. Although infection of these natural hosts does not lead to …
is a variety of small mammals. Although infection of these natural hosts does not lead to …
Borrelia burgdorferi OspC Protein Required Exclusively in a Crucial Early Stage of Mammalian Infection
K Tilly, JG Krum, A Bestor, MW Jewett… - Infection and …, 2006 - Am Soc Microbiol
This study demonstrates a strict temporal requirement for a virulence determinant of the
Lyme disease spirochete Borrelia burgdorferi during a unique point in its natural infection …
Lyme disease spirochete Borrelia burgdorferi during a unique point in its natural infection …
Physiological Osmotic Induction of Leptospira interrogans Adhesion: LigA and LigB Bind Extracellular Matrix Proteins and Fibrinogen
HA Choy, MM Kelley, TL Chen, AK Møller… - Infection and …, 2007 - Am Soc Microbiol
Transmission of leptospirosis occurs through contact of mucous membranes and abraded
skin with freshwater contaminated by pathogenic Leptospira spp. Exposure to physiological …
skin with freshwater contaminated by pathogenic Leptospira spp. Exposure to physiological …
The role of Borrelia burgdorferi outer surface proteins
MR Kenedy, TR Lenhart… - FEMS Immunology & …, 2012 - academic.oup.com
Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
[HTML][HTML] Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks
SM Dunham-Ems, MJ Caimano, U Pal… - The Journal of …, 2009 - Am Soc Clin Investig
Lyme disease is caused by transmission of the spirochete Borrelia burgdorferi from ticks to
humans. Although much is known about B. burgdorferi replication, the routes and …
humans. Although much is known about B. burgdorferi replication, the routes and …