Optimal interval to surgery after neoadjuvant chemoradiotherapy in rectal cancer: a systematic review and meta-analysis
D Du, Z Su, D Wang, W Liu, Z Wei - Clinical colorectal cancer, 2018 - Elsevier
This study aimed to evaluate the influence of a waiting interval of≥ 8 weeks between the
end of preoperative neoadjuvant chemoradiotherapy (nCRT) and surgery on the outcomes …
end of preoperative neoadjuvant chemoradiotherapy (nCRT) and surgery on the outcomes …
Meta-analysis of the effect of extending the interval after long-course chemoradiotherapy before surgery in locally advanced rectal cancer
Background The current standard of care in locally advanced rectal cancer (LARC) is
neoadjuvant long-course chemoradiotherapy (nCRT) followed by total mesorectal excision …
neoadjuvant long-course chemoradiotherapy (nCRT) followed by total mesorectal excision …
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial
J Garcia-Aguilar, OS Chow, DD Smith… - The Lancet …, 2015 - thelancet.com
Background Patients with locally advanced rectal cancer who achieve a pathological
complete response to neoadjuvant chemoradiation have an improved prognosis. The need …
complete response to neoadjuvant chemoradiation have an improved prognosis. The need …
Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
M Maas, PJ Nelemans, V Valentini, P Das… - The lancet …, 2010 - thelancet.com
Background Locally advanced rectal cancer is usually treated with preoperative
chemoradiation. After chemoradiation and surgery, 15–27% of the patients have no residual …
chemoradiation. After chemoradiation and surgery, 15–27% of the patients have no residual …
Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization
BACKGROUND: Complete tumor regression may develop after neoadjuvant chemoradiation
therapy for distal rectal cancer. Studies have suggested that selected patients with complete …
therapy for distal rectal cancer. Studies have suggested that selected patients with complete …
Optimal time interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer
DAM Sloothaak, DE Geijsen… - Journal of British …, 2013 - academic.oup.com
Background Neoadjuvant chemoradiotherapy (CRT) has been proven to increase local
control in rectal cancer, but the optimal interval between CRT and surgery is still unclear …
control in rectal cancer, but the optimal interval between CRT and surgery is still unclear …
Optimal timing of surgery after chemoradiation for advanced rectal cancer: preliminary results of a multicenter, nonrandomized phase II prospective trial
J Garcia-Aguilar, DD Smith, K Avila… - Annals of …, 2011 - journals.lww.com
Objective: To determine whether extending the interval between chemoradiation (CRT) and
surgery, and administering additional chemotherapy during the waiting period has an impact …
surgery, and administering additional chemotherapy during the waiting period has an impact …
Interim analysis of the Stockholm III trial of preoperative radiotherapy regimens for rectal cancer
D Pettersson, B Cedermark, T Holm… - Journal of British …, 2010 - academic.oup.com
Background To address issues regarding the fractionation of radiotherapy (RT) and timing of
surgery for rectal cancer, a multicentre trial has randomized patients to preoperative short …
surgery for rectal cancer, a multicentre trial has randomized patients to preoperative short …
Impact of preoperative radiotherapy on anastomotic leakage and stenosis after rectal cancer resection: post hoc analysis of a randomized controlled trial
Q Qin, T Ma, Y Deng, J Zheng, Z Zhou… - Diseases of the Colon …, 2016 - journals.lww.com
BACKGROUND: Evidence regarding the effect of preoperative radiotherapy on anastomotic
integrity remains conflicting in rectal cancer surgery. Prospective comparisons with …
integrity remains conflicting in rectal cancer surgery. Prospective comparisons with …
Organ preservation and survival by clinical response grade in patients with rectal cancer treated with total neoadjuvant therapy: a secondary analysis of the OPRA …
HM Thompson, DM Omer, S Lin, JK Kim… - JAMA Network …, 2024 - jamanetwork.com
Importance Assessing clinical tumor response following completion of total neoadjuvant
therapy (TNT) in patients with locally advanced rectal cancer is paramount to select patients …
therapy (TNT) in patients with locally advanced rectal cancer is paramount to select patients …