Alkoxy radicals are highly reactive species that have long been recognized as versatile
intermediates in organic synthesis. However, their development has long been impeded due …

C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

Catalytic C (sp3)–H functionalization has provided enormous opportunities to construct
organic molecules, facilitating the derivatization of complex pharmaceutical compounds …

The functionalization of C–H bonds in organic molecules containing functional groups has
been one of the holy grails of catalysis. One synthetically important approach to the diverse …

Abstract Frustrated Lewis pairs (FLPs) are well documented for the activation of small
molecules such as dihydrogen and carbon dioxide,,–. Although canonical FLP chemistry is …

Hydrogen-atom transfer (HAT) provides straightforward methods to generate open-shell
radical intermediates from RH (R= C, Si, etc.) bonds and offers unique opportunities for …

Organoboron compounds have important synthetic value and can be applied in numerous
transformations. The development of practical and convenient ways to synthesize boronate …

Borylations of inert carbon–hydrogen bonds are highly useful for transforming feedstock
chemicals into versatile organoboron reagents. Catalysis of these reactions has historically …

The intermediacy of alkoxy radicals in cerium-catalyzed C–H functionalization via H-atom
abstraction has been unambiguously confirmed. Catalytically relevant Ce (IV)–alkoxide …

The ability to selectively introduce diverse functionality onto hydrocarbons is of substantial
value in the synthesis of both small molecules and polymers. Herein, we report an approach …