Ankylosing spondylitis (AS) is an inflammatory autoimmune disease. AS is a prototype form
of spondyloarthropathies (SpA). The precise etiology of AS has not been fully understood …

Ankylosing spondylitis (AS) is a chronic inflammatory autoimmune disease, characterized by
typically an axial arthritis. AS is the prototype of a group of disorders called …

Abstract Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating
disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population. Current …

Ankylosing spondylitis (AS) is an autoimmune disease with a chronic inflammatory arthritis.
The critical role of methylation in the biology of immunocytes has increasingly been …

The HLA-B27 molecule is one of the most fascinating in medicine. Its contribution to the
aetiopathogenesis of SpA and other diseases, and its protective action in certain infections …

Ankylosing spondylitis (AS) is a highly heritable kind of arthritis that affects the vertebral
column. AS risk has been associated strongly with Human leukocyte antigen (HLA)-B* 27. In …

Methylation of DNA is one of the important regulatory mechanisms of gene transcription. B-
cell chronic lymphocytic leukemia/lymphoma 11B (BCL11B) plays a key role in the …

Objective To evaluate the efficacy, safety and tolerability of β-d-mannuronic acid (M2000) in
the treatment of ankylosing spondylitis (AS). Methods The study was a 12-week randomized …

Ankylosing Spondylitis (AS) is an inflammatory arthritis, which affects mainly spine and
sacroiliac joints. According to recent studies, ERAP1 is the second most common candidate …

Abstract Objective: Interleukin (IL)-23/IL-17 pathway involves in the pathogenesis of
ankylosing spondylitis (AS). The exact mechanism implicated in overexpression of IL-23 and …