Introduction Congenital chloride diarrhea (CLD) is a rare autosomal recessive disorder
characterized by watery diarrhea with a high level of fecal Cl−, metabolic alkalosis, and …

Congenital diarrheal disorders are a heterogeneous group of conditions characterized by
watery diarrhea that can potentially lead to massive life-threatening fluid and electrolyte …

Background Congenital chloride diarrhoea [CLD] is a rare autosomal recessive disease
caused by mutations in the solute family carrier 26 member 3 [SLC26A3] gene. Patients …

Introduction Congenital chloride diarrhoea (CCD) is an autosomal recessive condition that
causes secretory diarrhoea and potentially deadly electrolyte imbalances in infants because …

DRA (downregulated in adenoma, SLC26A3) and NHE3 (Na+/H+ exchanger 3, SLC9A3)
together mediate intestinal electroneutral NaCl absorption. Both transporters contain PDZ …

In Inflammatory Bowel Disease (IBD), malabsorption of electrolytes (NaCl) results in
diarrhea. Inhibition of coupled NaCl absorption, mediated by the dual operation of Na: H and …

Background Congenital chloride diarrhea (CCD, OMIM 214700) is a rare autosomal
recessively inherited condition characterized by watery diarrhea, hypochloremia and …

Congenital diarrheal disorders (CDDs) are early-onset enteropathies generally inherited as
autosomal recessive traits. Most patients with CDDs require rapid diagnosis as they need …

Congenital Chloride Diarrhea (CCD) is a rare autosomalrecessive disorder primarily
characterized by severe watery diarrhea and fecal loss of large amounts of chloride …

Congenital chloride diarrhea (CLD) is inherited as autosomal recessive trait, which is
caused by single gene mutation. 1 It is caused by a mutation of the solute carrier family 26 …