The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications
B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …
nature for millions of years. The human infection, named Chagas disease, is a major public …
Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Immunoregulatory networks in human C hagas disease
WO Dutra, CAS Menezes, LMD Magalhães… - Parasite …, 2014 - Wiley Online Library
Chagas disease, caused by the infection with T rypanosoma cruzi, is endemic in all L atin A
merica. Due to the increase in population migration, C hagas disease has spread worldwide …
merica. Due to the increase in population migration, C hagas disease has spread worldwide …
Chagas disease diagnostic applications: present knowledge and future steps
V Balouz, F Agüero, CA Buscaglia - Advances in parasitology, 2017 - Elsevier
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …
illness of major significance throughout Latin America and an emergent threat to global …
[HTML][HTML] Evidence for Trypanosoma cruzi in adipose tissue in human chronic Chagas disease
Trypanosoma cruzi the cause of Chagas disease persists in tissues of infected experimental
animals and humans. Here we demonstrate the persistence of the parasite in adipose tissue …
animals and humans. Here we demonstrate the persistence of the parasite in adipose tissue …
Multiplex Real-Time PCR Assay Using TaqMan Probes for the Identification of Trypanosoma cruzi DTUs in Biological and Clinical Samples
CI Cura, T Duffy, RH Lucero, M Bisio… - PLoS neglected …, 2015 - journals.plos.org
Background Trypanosoma cruzi has been classified into six Discrete Typing Units (DTUs),
designated as TcI–TcVI. In order to effectively use this standardized nomenclature, a …
designated as TcI–TcVI. In order to effectively use this standardized nomenclature, a …
Ecological scenario and Trypanosoma cruzi DTU characterization of a fatal acute Chagas disease case transmitted orally (Espírito Santo state, Brazil)
MA Dario, MS Rodrigues, JHS Barros, SCC Xavier… - Parasites & …, 2016 - Springer
Background Trypanosoma cruzi infection via oral route results in outbreaks or cases of acute
Chagas disease (ACD) in different Brazilian regions and poses a novel epidemiological …
Chagas disease (ACD) in different Brazilian regions and poses a novel epidemiological …
Putting infection dynamics at the heart of Chagas disease
MD Lewis, JM Kelly - Trends in parasitology, 2016 - cell.com
In chronic Trypanosoma cruzi infections, parasite burden is controlled by effective, but
nonsterilising immune responses. Infected cells are difficult to detect because they are …
nonsterilising immune responses. Infected cells are difficult to detect because they are …
Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU
Background Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided
into six discrete typing units (DTUs), named TcI-TcVI. TcII is among the major DTUs enrolled …
into six discrete typing units (DTUs), named TcI-TcVI. TcII is among the major DTUs enrolled …
A Simple Strain Typing Assay for Trypanosoma cruzi: Discrimination of Major Evolutionary Lineages from a Single Amplification Product
RO Cosentino, F Agüero - 2012 - journals.plos.org
Background Trypanosoma cruzi is the causative agent of Chagas' Disease. The parasite has
a complex population structure, with six major evolutionary lineages, some of which have …
a complex population structure, with six major evolutionary lineages, some of which have …