Platelet's plea to Immunologists: Please do not forget me
V Kumar, JH Stewart IV - International Immunopharmacology, 2024 - Elsevier
Platelets are non-nucleated mammalian cells originating from the cytoplasmic expulsion of
the megakaryocytes. Megakaryocytes develop during hematopoiesis through …
the megakaryocytes. Megakaryocytes develop during hematopoiesis through …
[HTML][HTML] How age affects human hematopoietic stem and progenitor cells and strategies to mitigate HSPC aging
X Li, J Wang, L Hu, T Cheng - Experimental Hematology, 2025 - Elsevier
Hematopoietic stem cells (HSCs) are central to blood formation and play a pivotal role in
hematopoietic and systemic aging. With aging, HSCs undergo significant functional …
hematopoietic and systemic aging. With aging, HSCs undergo significant functional …
Hematopoietic stem cell heterogeneity and age-related platelet bias: implications for bone marrow transplantation and blood disorders
Y Chen, J Shentu, H Lou, Y Xia, Y Jiang… - Stem Cell Research & …, 2024 - Springer
Hematopoietic stem cells (HSCs) are critical for maintaining lifelong blood production and
immune function, especially in the context of bone marrow transplantation, where their ability …
immune function, especially in the context of bone marrow transplantation, where their ability …
Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging
S Zhang, C Ayemoba, AM Di Staulo, K Joves… - Blood, 2024 - Elsevier
Hematopoietic stem cells (HSCs), responsible for blood cell production, and their bone
marrow regulatory niches undergo age-related changes, impacting immune responses and …
marrow regulatory niches undergo age-related changes, impacting immune responses and …
A rare HSC-derived megakaryocyte progenitor accumulates via enhanced survival and contributes to exacerbated thrombopoiesis upon aging
Distinct routes of cellular production from hematopoietic stem cells (HSCs) have defined our
current view of hematopoiesis. Recently, we challenged classical views of platelet …
current view of hematopoiesis. Recently, we challenged classical views of platelet …
Clonal analysis of murine HSC self-renewal and differentiation in native hematopoiesis
C You, Z Zhang, L Lin, J Sun - bioRxiv, 2024 - biorxiv.org
Hematopoietic stem cells (HSC) maintain lifelong hematopoiesis. However, in current clonal
analyses with unbiased" barcoding" approaches, steady-state hematopoietic clones in …
analyses with unbiased" barcoding" approaches, steady-state hematopoietic clones in …