Curcumin and cancer

A Giordano, G Tommonaro - Nutrients, 2019 - mdpi.com
Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

Phytochemicals in cancer treatment: From preclinical studies to clinical practice

AS Choudhari, PC Mandave, M Deshpande… - Frontiers in …, 2020 - frontiersin.org
Cancer is a severe health problem that continues to be a leading cause of death worldwide.
Increasing knowledge of the molecular mechanisms underlying cancer progression has led …

A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics

J Anjum, S Mitra, R Das, R Alam, A Mojumder… - Pharmacological …, 2022 - Elsevier
Abnormalities in the mitogen-activated protein kinase (MAPK) signaling pathway are a key
contributor to the carcinogenesis process and have therefore been implicated in several …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Status and challenges of plant-anticancer compounds in cancer treatment

P Garcia-Oliveira, P Otero, AG Pereira, F Chamorro… - Pharmaceuticals, 2021 - mdpi.com
Nowadays, cancer is one of the deadliest diseases in the world, which has been estimated
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …

Recent insights into the nutritional immunomodulation of cancer‐related microRNAs

TÖ Şahin, B Yılmaz, N Yeşilyurt, D Cicia… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the most common cause of death worldwide, following cardiovascular diseases.
Cancer is a multifactorial disease and many reasons such as physical, chemical, biological …

Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action

S Patra, B Pradhan, R Nayak, C Behera, S Das… - Phytomedicine, 2021 - Elsevier
Background Epidemiological studies has revealed that a diet rich in fruits and vegetables
could lower the risk of certain cancers. In this setting, natural polyphenols are potent …

Exosome-mediated metastasis: from epithelial–mesenchymal transition to escape from immunosurveillance

N Syn, L Wang, G Sethi, JP Thiery, BC Goh - Trends in pharmacological …, 2016 - cell.com
Exosomes are extracellular signalosomes that facilitate eukaryotic intercellular
communication under a wide range of normal physiological contexts. In malignancies, this …

[HTML][HTML] PDGF signaling pathway in hepatic fibrosis pathogenesis and therapeutics

HZ Ying, Q Chen, WY Zhang… - Molecular …, 2017 - … .spandidos-publications.com
The platelet‑derived growth factor (PDFG) signaling pathway exerts persistent activation in
response to a variety of stimuli and facilitates the progression of hepatic fibrosis. Since this …

[HTML][HTML] Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

JA McCubrey, K Lertpiriyapong, LS Steelman… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …