Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Management of moderate to severe traumatic brain injury: an update for the intensivist

G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive Care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Post-concussion symptoms and disability in adults with mild traumatic brain injury: a systematic review and meta-analysis

C Cancelliere, L Verville, JL Stubbs, H Yu… - Journal of …, 2023 - liebertpub.com
Studies investigating long-term symptoms and disability after mild traumatic brain injury
(mTBI) have yielded mixed results. This systematic review and meta-analysis aimed to …

Incremental prognostic value of acute serum biomarkers for functional outcome after traumatic brain injury (CENTER-TBI): an observational cohort study

IRAR Helmrich, E Czeiter, K Amrein, A Büki… - The Lancet …, 2022 - thelancet.com
Background Several studies have reported an association between serum biomarker values
and functional outcome following traumatic brain injury. We aimed to examine the …

A systematic review of treatments of post-concussion symptoms

C Heslot, P Azouvi, V Perdrieau, A Granger… - Journal of clinical …, 2022 - mdpi.com
Approximately 10–20% of patients who have sustained a mild Traumatic Brain Injury (mTBI)
show persistent post-concussion symptoms (PCS). This review aims to summarize the level …

Acute thalamic connectivity precedes chronic post-concussive symptoms in mild traumatic brain injury

RE Woodrow, S Winzeck, AI Luppi, IR Kelleher-Unger… - Brain, 2023 - academic.oup.com
Chronic post-concussive symptoms are common after mild traumatic brain injury (mTBI) and
are difficult to predict or treat. Thalamic functional integrity is particularly vulnerable in mTBI …

Prognostic models for global functional outcome and post-concussion symptoms following mild traumatic brain injury: a Collaborative European NeuroTrauma …

A Mikolić, EW Steyerberg, S Polinder… - Journal of …, 2023 - liebertpub.com
After mild traumatic brain injury (mTBI), a substantial proportion of individuals do not fully
recover on the Glasgow Outcome Scale Extended (GOSE) or experience persistent post …

Feasibility of concussion rehabilitation approaches tailored to psychological coping styles: a randomized controlled trial

ND Silverberg, M Cairncross, PMA Brasher… - Archives of physical …, 2022 - Elsevier
Objective To evaluate the feasibility of a clinical trial involving participants with concussion
randomized to treatments designed to address fear avoidance or endurance coping, which …

Neuroanatomical substrates and symptoms associated with magnetic resonance imaging of patients with mild traumatic brain injury

S Richter, S Winzeck, EN Kornaropoulos… - JAMA Network …, 2021 - jamanetwork.com
Importance Persistent symptoms after mild traumatic brain injury (mTBI) represent a major
public health problem. Objective To identify neuroanatomical substrates of mTBI and the …

Use of support vector machines approach via combat harmonized diffusion tensor imaging for the diagnosis and prognosis of mild traumatic brain injury: a CENTER …

M Siqueira Pinto, S Winzeck… - Journal of …, 2023 - liebertpub.com
The prediction of functional outcome after mild traumatic brain injury (mTBI) is challenging.
Conventional magnetic resonance imaging (MRI) does not do a good job of explaining the …