Pharmacotherapy in pediatric patients is challenging in view of the maturation of organ
systems and processes that affect pharmacokinetics and pharmacodynamics. Especially for …

This work is part two of a three-part series in this issue of a Sweden-United States
collaborative effort towards the understanding of the chemical attribution signatures of …

Organophosphorus (OP) compounds, which include insecticides and chemical warfare
nerve agents (CWNAs) such as sarin (GB) and VX, continue to be a global threat to both …

A recently proposed model for the incorporation of xenobiotics of forensic interest into the
human skeleton suggests nerve agent metabolites may incorporate into bone at relatively …

Animal research continues to serve a critical role in the testing and development of medical
countermeasures. The Göttingen minipig, developed for laboratory research, may provide …

Human butyrylcholinesterase (HuBChE) is under development for use as a pretreatment
antidote against nerve agent toxicity. Animals are used to evaluate the efficacy of HuBChE …

Animal models are essential for evaluating the toxicity of chemical warfare nerve agents
(CWNAs) to extrapolate to human risk and are necessary to evaluate the efficacy of medical …

摘要目的: 克隆西藏小型猪CYP3A 基因并与人及其它小型猪品种进行序列比对分析. 方法:
根据Genebank 数据库设计引物, 取西藏小型猪新鲜肝脏组织, Trizol 法提取肝脏总RNA …

The article contains the knowledge about the V-group of organophosphorus chemical
warfare agents, named nerve agents, used since their discovery until the year 1970. Group …

W pracy opisano grupę V fosforoorganicznych bojowych środków trujących (BST) o
działaniu paralityczno-drgawkowym stosowanych od ich odkrycia do 1970 roku. Grupa V …