[HTML][HTML] Aberrant structural and functional connectivity and neurodevelopmental impairment in preterm children
Background Despite advances in antenatal and neonatal care, preterm birth remains a
leading cause of neurological disabilities in children. Infants born prematurely, particularly …
leading cause of neurological disabilities in children. Infants born prematurely, particularly …
Redefining the endophenotype concept to accommodate transdiagnostic vulnerabilities and etiological complexity
TP Beauchaine, JN Constantino - Biomarkers in medicine, 2017 - Taylor & Francis
In psychopathology research, endophenotypes are a subset of biomarkers that indicate
genetic vulnerability independent of clinical state. To date, an explicit expectation is that …
genetic vulnerability independent of clinical state. To date, an explicit expectation is that …
Wrestling with social and behavioral genomics: risks, potential benefits, and ethical responsibility
In this consensus report by a diverse group of academics who conduct and/or are concerned
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …
about social and behavioral genomics (SBG) research, the authors recount the often‐ugly …
Irritability as a transdiagnostic vulnerability trait: Current issues and future directions
TP Beauchaine, JL Tackett - Behavior therapy, 2020 - Elsevier
In recent years, irritability has received increasing attention among mental health
professionals given its transdiagnostic associations with diverse forms of psychopathology …
professionals given its transdiagnostic associations with diverse forms of psychopathology …
Clinical and translational implications of an emerging developmental substructure for autism
JN Constantino, T Charman… - Annual review of clinical …, 2021 - annualreviews.org
A vast share of the population-attributable risk for autism relates to inherited polygenic risk. A
growing number of studies in the past five years have indicated that inherited susceptibility …
growing number of studies in the past five years have indicated that inherited susceptibility …
RDoC and psychopathology among youth: Misplaced assumptions and an agenda for future research
TP Beauchaine, SP Hinshaw - Journal of clinical child & …, 2020 - Taylor & Francis
Now over 10 years old, the Research Domain Criteria (RDoC) has gained impressive
traction in the adult psychopathology literature, but enthusiasm among child and adolescent …
traction in the adult psychopathology literature, but enthusiasm among child and adolescent …
Identification of neuropsychiatric copy number variants in a health care system population
Importance Population screening for medically relevant genomic variants that cause
diseases such as hereditary cancer and cardiovascular disorders is increasing to facilitate …
diseases such as hereditary cancer and cardiovascular disorders is increasing to facilitate …
Linking social motivation with social skill: The role of emotion dysregulation in autism spectrum disorder
Autism spectrum disorder (ASD) is associated with pervasive social deficits as well as
marked emotion dysregulation across the life span. Decreased social motivation accounts in …
marked emotion dysregulation across the life span. Decreased social motivation accounts in …
Psychiatry and developmental psychopathology: Unifying themes and future directions
TP Beauchaine, JN Constantino, EP Hayden - Comprehensive psychiatry, 2018 - Elsevier
In the past 35 years, developmental psychopathology has grown into a flourishing discipline
that shares a scientific agenda with contemporary psychiatry. In this editorial, which …
that shares a scientific agenda with contemporary psychiatry. In this editorial, which …
Deconstructing autism: from unitary syndrome to contributory developmental endophenotypes
JN Constantino - International Review of Psychiatry, 2018 - Taylor & Francis
A recent generation of family studies has revealed that autism can be predicted from an
array of neurobehavioural susceptibilities that are appreciable before the syndrome is …
array of neurobehavioural susceptibilities that are appreciable before the syndrome is …