Epigenetic dysregulation is increasingly appreciated as a hallmark of cancer, including
disease initiation, maintenance and therapy resistance. As a result, there have been …

Epigenetic modulators perform critical functions in gene expression for rapid adaption to
external stimuli and are prevalent in all higher-order organisms. The establishment of a link …

Diffuse large B cell lymphoma (DLBCL) is one of the most common yet aggressive types of B
cell lymphoma and remains incurable in 40% of patients. Herein, we profile the …

Adult T-cell leukemia/lymphoma (ATL) is an aggressive neoplasm immunophenotypically
resembling regulatory T cells, associated with human T-cell leukemia virus type-1. Here, we …

Single-cell multi-omics technologies have revolutionized cancer research by allowing us to
examine individual cells at a molecular level. Unlike traditional bulk omics approaches …

Follicular lymphoma (FL) is clinically heterogeneous, with select patients tolerating extended
watch-and-wait, whereas others require prompt treatment, suffer progression of disease …

Diffuse large B cell lymphoma (DLBCL) is one of the most common types of aggressive
lymphoid malignancies. Here, we explore the contribution of RNA editing to DLBCL …

Careful histopathologic examination remains the cornerstone in the diagnosis of the
clinically and biologically heterogeneous group of lymphoid malignancies. However, recent …

The biological role of the repetitive DNA sequences in the human genome remains an
outstanding question. Recent long-read human genome assemblies have allowed us to …

Tumor cells can result from gene mutations and over-expression. Synthetic lethality (SL)
offers a desirable setting where cancer cells bearing one mutated gene of an SL gene pair …