Plant extracts for type 2 diabetes: From traditional medicine to modern drug discovery

J Lee, S Noh, S Lim, B Kim - Antioxidants, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is one of the largest public health problems worldwide.
Insulin resistance-related metabolic dysfunction and chronic hyperglycemia result in …

Diet‐induced rodent models of obesity‐related metabolic disorders—a guide to a translational perspective

I Preguiça, A Alves, S Nunes, R Fernandes… - Obesity …, 2020 - Wiley Online Library
Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

Ginger root extract improves GI health in diabetic rats by improving intestinal integrity and mitochondrial function

R Wang, JM Santos, JM Dufour, ER Stephens… - Nutrients, 2022 - mdpi.com
Background Emerging research suggests hyperglycemia can increase intestinal
permeability. Ginger and its bioactive compounds have been reported to benefit diabetic …

In Vivo Studies of Inoculated Plants and In Vitro Studies Utilizing Methanolic Extracts of Endophytic Streptomyces sp. Strain DBT34 Obtained from Mirabilis jalapa L …

AK Passari, VV Leo, G Singh, L Samanta… - International journal of …, 2020 - mdpi.com
Reactive oxygen species (ROS) and other free radicals cause oxidative damage in cells
under biotic and abiotic stress. Endophytic microorganisms reside in the internal tissues of …

Ginger alleviates mechanical hypersensitivity and anxio-depressive behavior in rats with diabetic neuropathy through beneficial actions on gut microbiome …

CL Shen, R Wang, JM Santos, MM Elmassry… - Nutrition Research, 2024 - Elsevier
The relationship among gut microbiota, mitochondrial dysfunction/neuroinflammation, and
diabetic neuropathic pain (DNP) has received increased attention. Ginger has antidiabetic …

Downregulation of candidate gene expression and neuroprotection by piperine in streptozotocin-induced hyperglycemia and memory impairment in rats

S Kumar, S Chowdhury, A Razdan, D Kumari… - Frontiers in …, 2021 - frontiersin.org
There is accumulating evidence showing that hyperglycemia conditions like diabetes
possess a greater risk of impairment to the neuronal system because high glucose levels …

Polyphenol-rich black currant and cornelian cherry juices ameliorate metabolic syndrome induced by a high-fat high-fructose diet in Wistar rats

M Paunovic, M Milosevic, O Mitrovic-Ajtic, N Velickovic… - Heliyon, 2024 - cell.com
Diets high in fat and sugar lead to metabolic syndrome (MetS) and related chronic diseases.
We investigated the effects of commercially available, cold-pressed polyphenol-rich black …

Mitigation of lens opacification by a functional food in a diabetic rodent model

KK Kalahasti, CU Kumar, M Nagaraju… - Chemico-Biological …, 2024 - Elsevier
The current study was designed to test a functional food (FF) mixture containing aldose
reductase inhibitors and antiglycation bioactive compounds for suppressing the onset and …

Functional Food Mixture Extricates D-Galactose-Induced Skeletal Muscle Impairment in Rats

M Nagaraju, P Savitikadi, KK Kalahasti… - Rejuvenation …, 2024 - liebertpub.com
Aging-related muscle atrophy/sarcopenia is the most common type of muscle impairment
that affects the quality of life. In the current study, we examined the effect of a functional food …

Effect of ginger on zinc, lipid profile and antioxidants levels in blood and liver of streptozotocin induced diabetic rats fed on zinc deficiency diet

I Tebboub, Z Kechrid - Indian Journal of Experimental Biology (IJEB), 2021 - or.niscpr.res.in
Diabetes mellitus is a non-communicable disease affecting 463 million people across the
world. Ginger has enormous health promoting potential effects in number of ailments …