Are cannabidiol and Δ9‐tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review
JM McPartland, M Duncan, V Di Marzo… - British journal of …, 2015 - Wiley Online Library
Based upon evidence that the therapeutic properties of C annabis preparations are not
solely dependent upon the presence of Δ9‐tetrahydrocannabinol (THC), pharmacological …
solely dependent upon the presence of Δ9‐tetrahydrocannabinol (THC), pharmacological …
[HTML][HTML] Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol
The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its
psychotropic and mind-altering side effects for millennia. There has been growing attention …
psychotropic and mind-altering side effects for millennia. There has been growing attention …
[HTML][HTML] In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease
Alzheimer's disease (AD) is a debilitating neurodegenerative disease that is affecting an
increasing number of people. It is characterized by the accumulation of amyloid-β and tau …
increasing number of people. It is characterized by the accumulation of amyloid-β and tau …
[HTML][HTML] Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD
Impairment of working memory is one of the most important deleterious effects of marijuana
intoxication in humans, but its underlying mechanisms are presently unknown. Here, we …
intoxication in humans, but its underlying mechanisms are presently unknown. Here, we …
[HTML][HTML] Opposite effects of Δ-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology
S Bhattacharyya, PD Morrison, P Fusar-Poli… - …, 2010 - nature.com
Abstract Δ-9-tetrahydrocannabinol (Δ-9-THC) and Cannabidiol (CBD), the two main
ingredients of the Cannabis sativa plant have distinct symptomatic and behavioral effects …
ingredients of the Cannabis sativa plant have distinct symptomatic and behavioral effects …
A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol
E Russo, GW Guy - Medical hypotheses, 2006 - Elsevier
This study examines the current knowledge of physiological and clinical effects of
tetrahydrocannabinol (THC) and cannabidiol (CBD) and presents a rationale for their …
tetrahydrocannabinol (THC) and cannabidiol (CBD) and presents a rationale for their …
What are the specific vs. generalized effects of drugs of abuse on neuropsychological performance?
MJ Fernandez-Serrano, M Pérez-García… - Neuroscience & …, 2011 - Elsevier
Most substance abusers simultaneously use and abuse more than one substance, even
when there is a clear drug of choice. This pattern creates a great challenge in relating …
when there is a clear drug of choice. This pattern creates a great challenge in relating …
The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
Cannabidiol (CBD), the main non-psychotomimetic component of the plant Cannabis sativa,
exerts therapeutically promising effects on human mental health such as inhibition of …
exerts therapeutically promising effects on human mental health such as inhibition of …
[HTML][HTML] Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic
E Aso, I Ferrer - Frontiers in pharmacology, 2014 - frontiersin.org
The limited effectiveness of current therapies against Alzheimer's disease (AD) highlights
the need for intensifying research efforts devoted to developing new agents for preventing or …
the need for intensifying research efforts devoted to developing new agents for preventing or …
5‐HT1A receptors are involved in the cannabidiol‐induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats
LBM Resstel, RF Tavares, SFS Lisboa… - British journal of …, 2009 - Wiley Online Library
Background and purpose: Cannabidiol (CBD) is a non‐psychotomimetic compound from
Cannabis sativa which induces anxiolytic‐and antipsychotic‐like effects in rodents. These …
Cannabis sativa which induces anxiolytic‐and antipsychotic‐like effects in rodents. These …