Tuberculosis (TB) is still the number one cause of death due to an infectious disease.
Pharmacokinetics and pharmacodynamics of anti-TB drugs are key in the optimization of TB …

Pott's spine, commonly known as spinal tuberculosis (TB), is an extrapulmonary form of TB
caused by Mycobacterium TB. Pott's paraplegia occurs when the spine is involved. Spinal …

Introduction Therapeutic drug monitoring (TDM) has been recommended for treatment
optimization in tuberculosis (TB) but is only is used in certain countries eg USA, Germany …

The prolonged treatment duration for multidrug-resistant tuberculosis (MDR-TB) makes
linezolid dosing difficult because of adverse effects associated with long-term use. We …

The cell envelope of Gram-negative bacteria belonging to the Burkholderia cepacia complex
(Bcc) presents unique restrictions to antibiotic penetration. As a consequence, Bcc species …

Background Cycloserine, or its structural analogue terizidone, has been associated with
neuropsychiatric toxicity (psychosis, depression, and neuropathy). Prospective clinical data …

Although cycloserine is a recommended drug for the treatment of multidrug-resistant
tuberculosis (MDR-TB) according to World Health Organization (WHO), few studies have …

Acyldepsipeptides (ADEPs) are a new class of emerging antimicrobial peptides (AMPs),
which are currently explored for treatment of pathogenic infections, including tuberculosis …

Objectives This study aimed to investigate the association between drug exposure and
adverse events (AEs) during the standardized multidrug-resistant tuberculosis (MDR-TB) …

Purpose Therapeutic drug monitoring (TDM) is a standard clinical procedure that uses the
pharmacokinetic and pharmacodynamic parameters of the drug in the body to determine the …