Gut barrier disruption and chronic disease

J Martel, SH Chang, YF Ko, TL Hwang… - Trends in Endocrinology …, 2022 - cell.com
The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …

Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

X Wang, Z Wang, J Cao, Y Dong, Y Chen - Microbiome, 2023 - Springer
Background Sleep loss is a serious global health concern. Consequences include memory
deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can …

[HTML][HTML] Gut microbiota: an important player in type 2 diabetes mellitus

Z Zhou, B Sun, D Yu, C Zhu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is one of the common metabolic diseases in the world. Due
to the rise in morbidity and mortality, it has become a global health problem. To date, T2DM …

Microbiota-derived metabolites as drivers of gut–brain communication

H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen… - Gut …, 2022 - Taylor & Francis
Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …

Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …

J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

[HTML][HTML] Diet and the microbiota–gut–brain axis: sowing the seeds of good mental health

K Berding, K Vlckova, W Marx, H Schellekens… - Advances in …, 2021 - Elsevier
Over the past decade, the gut microbiota has emerged as a key component in regulating
brain processes and behavior. Diet is one of the major factors involved in shaping the gut …

[HTML][HTML] Interplay between exercise and gut microbiome in the context of human health and performance

M Clauss, P Gérard, A Mosca, M Leclerc - Frontiers in nutrition, 2021 - frontiersin.org
Gut microbiota and exercise have recently been shown to be interconnected. Both moderate
and intense exercise are typically part of the training regimen of endurance athletes, but they …

Effects of nano-and microplastics on kidney: physicochemical properties, bioaccumulation, oxidative stress and immunoreaction

X Meng, J Zhang, W Wang, G Gonzalez-Gil… - Chemosphere, 2022 - Elsevier
The potential toxicity of nanoplastics (NPs) and microplastics (MPs) has raised concerns.
However, knowledge of the effects of NPs/MPs on the health of mammals is still limited. Here …

[HTML][HTML] The microbiota in cirrhosis and its role in hepatic decompensation

J Trebicka, J Macnaughtan, B Schnabl… - Journal of …, 2021 - Elsevier
Cirrhosis–the common end-stage of chronic liver disease–is associated with a cascade of
events, of which intestinal bacterial overgrowth and dysbiosis are central. Bacterial toxins …