Natural product derivatives are essential in searching for compounds with important
chemical, biological, and medical applications. Naphthoquinones are secondary …

Redox homeostasis is an equilibrium between reducing and oxidizing reactions within cells.
It is an essential, dynamic process, which allows proper cellular reactions and regulates …

Trypanosoma cruzi (T. cruzi) is a parasite that affects humans and other mammals. T. cruzi
depends on glycolysis as a source of adenosine triphosphate (ATP) supply, and …

Quinones are attractive pharmacological scaffolds for developing new agents for the
treatment of different transmissible and non-transmissible human diseases due to their …

American trypanosomiasis or Chagas disease, caused by Trypanosoma cruzi (T. cruzi),
affects approximately 6–7 million people worldwide. However, its pharmacological treatment …

Leishmania mexicana (L. mexicana) is a causal agent of cutaneous leishmaniasis (CL), a
“Neglected disease”, for which the search for new drugs is a priority. Benzimidazole is a …

Infectious diseases caused by trypanosomatids, including African trypanosomiasis (sleeping
sickness), Chagas disease, and different forms of leishmaniasis, are Neglected Tropical …

Protozoan parasites represent a significant risk for public health worldwide, afflicting
particularly people in more vulnerable categories and cause large morbidity and heavy …

Background Parasitic diseases are a public health problem despite the existence of drugs
for their treatment. These treatments have variable efficacy and, in some cases, serious …

An eco‐friendly electrochemical halogenation of 2‐amino‐1, 4‐naphthoquinones has been
developed. The new mild and energy efficient methodology comprises sustainable features …