Cell survival depends on essential processes in mitochondria. Various proteases within
these organelles regulate mitochondrial biogenesis and ensure the complete degradation of …

Abstract F 1 F 0-ATP synthases are multimeric protein complexes and common prerequisites
for their correct assembly are (i) provision of subunits in appropriate relative amounts,(ii) …

The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

YidC of Echerichia coli, a member of the conserved Alb3/Oxa1/YidC family, is postulated to
be important for biogenesis of membrane proteins. Here, we use as a model the lactose …

The integrity of the inner membrane of mitochondria is maintained by a membrane-
embedded quality control system that ensures the removal of misfolded membrane proteins …

Multiple or pleiotropic drug resistance most often occurs in Saccharomyces cerevisiae due
to substitution mutations within the Cys 6-Zn (II) transcription factors Pdr1p and Pdr3p. These …

The Escherichia coli inner membrane protein (IMP) YidC is involved in the membrane
integration of IMPs both in concert with and independently from the Sec translocase. YidC …

Saccharomyces cerevisiae Mdm38 and Ylh47 are homologues of human Letm1, a protein
implicated in Wolf-Hirschhorn syndrome. We analyzed the function of Mdm38 and Ylh47 in …

The inner membrane of mitochondria is one of the protein's richest cellular membranes. The
biogenesis of the respiratory chain and ATP-synthase complexes present in this membrane …

Significance: Mitochondria are complex dynamic organelles pivotal for cellular physiology
and human health. Failure to maintain mitochondrial health leads to numerous maladies that …