Changes in aging bone that lead to osteoporosis are mediated at multiple levels, including
hormonal alterations, skeletal unloading, and accumulation of senescent cells. This …

Marrow adipocytes, collectively termed marrow adipose tissue (MAT), reside in the bone
marrow in close contact to bone cells and haematopoietic cells. Marrow adipocytes arise …

Context: There is growing interest in the relationship between bone mineral density, bone
strength, and fat depots. Marrow adipose tissue, a well-established component of the …

With growing interest in the connection between fat and bone, there has been increased
investigation of the relationship with marrow fat in particular. Clinical research has been …

The bone marrow niche is a dynamic and complex microenvironment that can both regulate,
and be regulated by the bone matrix. Within the bone marrow (BM), mesenchymal stromal …

Bone marrow adipose tissue (MAT) is distinct from white adipose tissue (WAT) or brown
adipose tissue (BAT) for its location, feature and function. As a largely ignored adipose …

OBJECTIVE Vertebral compression fractures (VCFs) in patients with spinal metastasis can
lead to destabilization and often carry a high risk profile. It is therefore important to have …

Osteoporosis is characterized by a decreased bone mass and quality resulting in an
increased fracture risk. Quantitative imaging methods are critical in the diagnosis and follow …

Osteoporosis (OP) is a major global health concern, with aging being one of the most
important risk factors. Osteoarthritis (OA) is also an age-related disorder. Patients with OP …

Osteoporosis is a common disease, particularly prevalent in geriatric populations, which
causes significant worldwide morbidity due to increased bone fragility and fracture risk …